Sr. Scientific Lab Operations Manager

At RayzeBio, every day is an opportunity to ignite meaningful change. As a wholly-owned subsidiary of Bristol Myers Squibb, RayzeBio blends the nimble, pioneering spirit of an emergent biotech with the global expertise and resources of a leading innovator in oncology. Our mission is to develop transformative radiopharmaceutical therapies that offer new hope for patients living with cancer. Here, you’ll join a multidisciplinary team where your ideas are valued, your expertise is amplified, and collaboration is at the heart of everything we do. From day one, expect to make an immediate impact—on our science, on our teams, and most importantly, on patients. Learn more about RayzeBio: https://careers.bms.com/rayzebio/

Background

RayzeBio, a Bristol Myers Squibb company, is a dynamic biotechnology company headquartered in San Diego, CA. The company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. RayzeBio is developing innovative drugs against targets of solid tumors. Led by a successful and experienced entrepreneurial team, RayzeBio aims to be the global leader in radiopharmaceuticals

Job Description

We are seeking a highly motivated, scientifically trained Senior Scientific Lab Operations Manager to lead laboratory operations and partner strategically with the R&D team. This role combines scientific expertise with operational excellence to optimize inventory, study workflows, instrument utilization, and research productivity. The ideal candidate has experience in molecular biology, cell biology, or chemistry lab operations; understands common research instrumentation; and proactively improves laboratory efficiency while maintaining a safe, compliant environment.

The ideal candidate combines deep scientific experience with operational leadership and serves as a trusted partner to Discovery scientists. This individual is expected to proactively identify opportunities to improve laboratory infrastructure, operational efficiency, and scientific productivity while ensuring a safe, compliant, and collaborative research environment.

Job Responsibilities

Essential duties and responsibilities include the following; other duties may be assigned.

• Partner with Discovery leadership to anticipate laboratory needs and develop scalable operational plans aligned with current and future research priorities.
• Establish standardized procedures and workflows that improve efficiency, quality, reproducibility, and compliance.
• Manage laboratory budgets, capital planning, forecasting, service contracts, and CAPEX/non-CAPEX purchases in alignment with scientific needs.
• Lead laboratory infrastructure projects, including expansions, renovations, equipment installations, relocations, and space planning.
• Drive continuous improvement by identifying operational bottlenecks, implementing sustainable solutions, and monitoring relevant laboratory KPIs.
• Collaborate with EHS, Facilities, IT, Procurement, Scientific Leadership, and the RSO to maintain safe, compliant, and uninterrupted laboratory operations.
• Serve as the primary point of contact for laboratory operational and technical issues, including equipment malfunctions and service coordination.
• Oversee equipment lifecycle management, including selection, installation, calibration, preventive maintenance, repairs, vendor management, and record retention.
• Manage laboratory systems and platforms for inventory, consumable ordering, training, purchase orders, and LIMS-related workflows.
• Anticipate study needs and maintain appropriate inventory, equipment readiness, and laboratory capacity to support daily research activities.
• Coordinate onboarding for new scientists, including laboratory access, training, workspace preparation, and equipment readiness.
• Evaluate emerging laboratory technologies and recommend tools that improve scientific productivity and operational efficiency.
• Support audit and inspection readiness, including required documentation and laboratory records.
• Organize cross-functional laboratory meetings, track actions, and ensure timely follow-up.
• Manage refrigerators, freezers, tissue culture equipment, cleaning schedules, and decontamination of BSCs and incubators.
• Coordinate radioactive waste pickup and other hot-lab operational activities with the RSO.

Education and Experience

• BS in Life Sciences, Molecular Biology, Cell Biology, Chemistry, Biochemistry, or a related scientific discipline with a minimum of 12 years of experience as a scientist, inclu