Associate Scientist II, Analytical Development (Proteins)

About Forge  

Forge, a member of Ajinomoto Bio-Pharma Services, is a gene therapy development engine, focused on enabling access to life changing gene therapies and helping bring them from idea into reality. We partner with innovators in the gene therapy community: scientists, physicians, biotech/pharma companies, and patient groups. We bring expertise in gene therapy manufacturing and therapeutics development to the table, helping to champion teams that are navigating the long road from the lab bench to the bedside. Our goal is simple but vital to patients living with disease, and we take it seriously. With a patient-first approach, we are forging new models for working together to better accelerate these transformative medicines to reach those who need them the most.   

Forge is based in Columbus, Ohio, in a 200,000 square foot facility known affectionately by team members as, the Hearth. The Hearth, is a custom-designed cGMP facility dedicated to AAV manufacturing and hosts scalable, end-to-end manufacturing services.  

 

About the Role:

The Associate Scientist II, Analytical Development (Protein-Based Assays) supports the development and optimization of protein-based assays for AAV gene therapy products. This position is responsible for the execution of complex protein-based assays, contributing to method development, and collaborating with cross-functional teams to ensure the quality and consistency of our AAV gene therapy products. This role offers an excellent opportunity to gain hands-on experience in the critical analytical aspects of gene therapy development.

What You'll Do:

• Lead the execution of complex protein-based assays independently and troubleshoot technical issues.         
• Develop and optimize protein-based assays, including assay design, protocol development, and validation.
• Collaborate with scientists to analyze and interpret experimental data.
• Mentor and provide guidance to junior team members.
• Contribute to assay transfer activities between teams or sites.
• Participate in project planning and ensure timely delivery of results.       
• Assist in the preparation of regulatory documents and support regulatory submissions.    
• Stay current with industry trends and incorporate best practices into assay development.                 
• Implement quality control measures to ensure the reliability and robustness of assays.     
• Actively engage in continuous improvement efforts for processes and methodologies.

What You'll Bring:

• Bachelor's or Master's degree in a relevant scientific field (e.g., biology, biochemistry, molecular biology).
• Proficiency in advanced laboratory techniques related to protein-based assays.  
• Experience with assay development and optimization.                
• Ability to troubleshoot technical issues and recommend solutions.
• Strong data analysis skills and the ability to generate actionable insights from experimental results.

 

Work Environment and Physical Demands:  

This position works in both a laboratory environment and typical office environment where the physical work demands will vary depending on the specific tasks and duties required of the job. The employee will be stationary (standing/sitting) for extended periods of time. Employees regularly wear personal protective equipment based on the task being performed. Must be able to work in a confined space, such as a clean room or laboratory environment. Ability to identify small details within the field of vision, distinguish between different colors, and accurately identify objects within a specific area. 

 

This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee. Duties, responsibilities and activities may change or new ones may be assigned. 

 

Forge Biologics is an equal opportunity employer dedicated to building an inclusive and diverse workforce. Forge Biologics, provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran sta