Sr. GMP Manufacturing Technician - Marcus Center for Cellular Cures (CCBB)

School of Medicine

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

The Marcus Center for Cellular Cures (MC3) https://marcuscenter.duke.edu/ has an exciting growth opportunity for a motivated individual to fill a Sr. GMP Manufacturing Technician in their Carolina Cord Blood Bank Lab. The position is located at 2400 Pratt Street, Durham, N.C. Work hours for this position are primarily Tuesday-Friday – 10:30 am – 7:00 pm and Saturday 8:30 am – 5:00 pm.

The Marcus Center’s mission and values are listed below:

MC3 Vision: To live in a world where every person has access to high quality and effective cell based therapies

MC3 Mission: Together we design, develop and deliver the highest quality cellular therapies to improve health

 

Occupational Summary

Coordinate and participate in a variety of clerical and laboratory duties of a complex and technical nature in support of the receipt, processing, purification, analysis, and cryopreservation of hematopoietic cells obtained from umbilical cord blood, for hematopoietic stem cell transplantation.

The individual filling this position will be an integral member of a team of physicians, nurses, collection specialists, and other professionals providing cord blood collection and processing services for the Carolinas Cord Blood Bank.

 

Work Performed

Perform a variety of complex, technical duties involved in the manufacture of licensed DUCORD product from collected umbilical cord blood.  Utilize a biological safety cabinet and employ aseptic technique while conducting and participating in the processing, and cryopreservation of hematopoietic stem cells obtained from umbilical cord blood.  

Operate manual and automatic laboratory equipment used to count cells; stain cells; separate cells; wash cells; separate plasma, red cells, buffy coats, mononuclear cell populations and stem cells; and cryopreserve cells according to standard operating procedures for the Carolinas Cord Blood Bank. Perform ABO/Rh blood typing of cord blood units. Unload BacT/Alert and print sterility reports. Confirm units for removal from inventory post exclusion from banking.  Assist with removal of segments for confirmatory typing and shipping of prepared samples.  Print IDM results.  Perform cleaning, maintenance and qualitycontrolon equipment and reagents.

Receive and prepare cord blood unit and associated documents from local and remote collection sites; execute administrative functionstoprepare cord blood units for processing. Receive and prepare maternal samples and associated documents from local and remote collection sites; prepare maternal samples for shipment to the testing facility for infectious disease testing.  Unload and return cord blood shipping containers to remote collection sites.

Coordinate and participate in the preparation of culture media, chemicals, antibodies, pharmaceuticals, reagents, and solutions necessary for cell processing and cryopreservation.

Complete laboratory data forms and enter them into the electronic database for the bank. Prepare cord blood unit working and confidential files for administrative, technical, and medical review. Continually review and file paperwork and test results into the working file, ensuring that the file is completed and finished according to standard operating procedures.  In collabor