Senior Director, Global Medical Affairs, Oncology (Neuro-Oncology)

If you are a current Jazz employee please apply via the Internal Career site

Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit www.jazzpharmaceuticals.com for more information.

Job Description

Senior Director, Global Medical Affairs Molecule Lead (GMAL)
Therapeutic Area: Neuro-oncology

The Senior Director, Global Medical Affairs Molecule Lead (GMAL) will serve as the global medical affairs leader for Neuro-oncology within Jazz Pharmaceuticals’ oncology portfolio. This strategic role requires deep clinical expertise in neuro-oncology and extensive global medical affairs experience. Experience with rare diseases, paediatric oncology also an advantage.

As a senior member of the Global Medical and Scientific Affairs (GMSA) organization, the GMAL will report directly to the Therapy Area Head, Oncology. The successful candidate will be responsible for developing and executing the annual and long-range Global Medical Plans, including integrated evidence generation strategies, and ensuring strategic alignment with Franchise and Global Product Team (GPT) objectives.

This individual must demonstrate exceptional medical leadership, cross-functional collaboration, and strong communication skills, partnering closely with global and regional colleagues across Medical Affairs, Clinical Development, Commercial, Regulatory, and Market Access.

Key Responsibilities:

• Lead the development and execution of annual and long-range Global Medical Plans and evidence generation strategies for the asset

• Translate clinical and scientific insights into robust, cross-functional medical strategies

• Chair the Medical Functional Matrix Team (FMT) for the asset, driving coordination and excellence across global medical functions

• Collaborate with Clinical Scientists, Real-World Evidence leads, and Global Health Outcomes teams to co-develop protocols, synopses, and study execution plans

• Build impactful scientific platforms and narratives that support the neuro-oncology strategy and product positioning

• Develop and execute the global medical communications strategy, including a comprehensive publication plan

• Partner with Medical Communications to create core materials (e.g., training decks, study summaries) for global and regional dissemination

• Engage with Clinical Development to ensure evidence gaps are addressed within study designs and lifecycle planning

• Collaborate with Commercial to support launch readiness and product lifecycle management

• Represent Global Medical Affairs as the primary voice in cross-functional teams such as GPT and Clinical Development Team

• Demonstrate subject matter expertise in neuro-oncology and maintain current scientific and clinical knowledge

• Assess competitive landscape and contribute strategic insights into the evolution of neuro-oncology treatment paradigms

• Drive external stakeholder engagement, including expert mapping, development planning, and advisory boards

• Lead external scientific society interactions and identify potential collaborative opportunities

• Support patient advocacy strategy development in partnership with Global Advocacy teams

• Shape the Investigator-Sponsored Trial (IST) and collaborative research strategy for the asset

Required Knowledge, Skills & Abilities:

• Strong clinical background in neuro-oncology

• Minimum of 7 years’ experience in Medical Affairs, with demonstrated success in a strategic global role

• Proven ability to develop and execute medical strategies that driv