Jobs and Careers
EL

Senior Principal Engineer - Automation Engineering – Systems and Digital Integration

Eli Lilly and Company
United Statesfull_timeVerifiedPosted 5 Feb 2026
💰 $181,500/yr($114,000/yr$181,500/yr)

About the role

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Lilly recently announced a $4.5 billion investment to create the Lilly Medicine Foundry, a new center for advanced manufacturing and drug development. The first-ever facility of its kind, combining research and manufacturing in a single location, the Medicine Foundry will allow Lilly to further develop innovative solutions to optimize manufacturing processes and increase capacity for clinical trial medicines, while also reducing costs and environmental impact.

The Senior Principal Engineer - Automation Engineering will work as a member of the Automation Engineering Department at Eli Lilly, Foundry. The engineer will provide automation support for one or more operating areas across site and/or for capital projects. Process Automation is core to delivering a right first time facility start up and continued support of ongoing manufacturing operations into the future. 

The Senior Principal Engineer is also responsible for the productivity and mentorship of the employees with the purpose of ensuring that reliable and compliant control applications and systems are used in the manufacturing at Foundry.  Additionally, the Senior Principal Engineer as a key technical expert with partners to influence and implement within the process control organization and across functional disciplines to support the process control technical agenda, business plan priorities, and compliance objectives. 

In the project delivery phase and startup phase of the project (startup expected 2025 to 2028), automation engineering roles will be fluid and dynamic as we endeavor to support the project delivery, build a new organization, develop and implement the necessary systems and business processes required to support GMP operations, and build the site culture. This will require significant collaboration, creativity and resilience as the site grows to a full scale GMP manufacturing through start up. 

 

Key Objectives/Deliverables: 

Technical Leadership 

Mentor process control team, including design, controls philosophy, implementation and commissioning 

• Process control work implementation and coordination 

• Develop and implement the Automation Engineering Project Plan. 

 

Operational Excellence 

• Technically lead and oversee the work of Site Area leads and System Integrator including Functional Requirements, Design Specifications, DCS Application Software, Test Specifications. 

• Lead/Participate in design reviews and Automation application software reviews, attend equipment and software FATs 

• Lead a team of automation engineers supporting commissioning 

• Provide periodic status updates to Project Management 

• Devising functional requirements and process control strategies for control systems in collaboration with Process Engineering 

• DCS software design, coding/configuration and testing (sequence logic, graphics, batch software etc.) 

Automation Engineering including design, tuning and troubleshooting of system

Apply for this role

Generate a tailored application kit with a matched cover letter, interview prep, and CV highlights — in under 60 seconds.

Apply Now →Generate Application Kit

Free account required — sign up in 30s

Company

Eli Lilly and Company

View company profile →