Director, Patient Centered Science, Late CVRM

The Patient Centered Science (PCS) Director leads therapy area and project-level patient-centered evidence strategies, with a focus on clinical outcome assessments (COAs), patient-reported outcomes (PROs), and broader patient experience data across the product lifecycle.  

The role ensures that patient-centered evidence is fit for purpose and supports regulatory approval, HTA/reimbursement needs, and commercialization. 

The role holder partners with cross-functional teams to define the most appropriate COA/PRO endpoints, identify evidence gaps, and recommend or develop instruments and methods that capture the patient experience and meet stakeholder expectations. They provide strategic leadership from early development through late-stage programs, ensuring that patient-centered evidence is integrated into clinical plans, TPPs/TPCs, regulatory discussions, and submission dossiers. 

The PCS Director is accountable for leading patient input activities, including interviews and related evidence-generation approaches, and for translating those insights into scientifically robust recommendations. The role also represents PCS in interactions with regulatory authorities, HTA bodies, external experts, and internal governance teams, while supporting payer evidence needs such as utility and patient preference measurement. 

In addition, the PCS Director drives consistent TA-level standards for PRO/COA strategy, oversees relevant vendors and subprojects, contributes to scientific communications and publications, and strengthens AstraZeneca’s external reputation in patient-centered measurement science. 

Key Responsibilities