Jobs and Careers

Senior Director, US Medical Lead LC-FAOD and MPSs

Ultragenyx

United States - Remote, United StatesRemotefull_timeVerifiedPosted 18 Aug 2026

💰 $334,100/yr($270,500/yr – $334,100/yr)

About the role

Why Join Us?

Be a hero for our rare disease patients

At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do. To achieve this goal, our vision is to lead the future of rare disease medicine. For us, this means going where other biopharma companies won’t go – challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life-changing treatments. We do this by following the science, applying a novel rapid development approach, making innovative medicines at fair and reasonable prices, and creating a collaborative ecosystem to reach patients in ways that are most meaningful for them.

Our commitment and care for patients extends to our people, so culture is an essential cornerstone for Ultragenyx. We remain continuously focused on creating a supportive and inclusive environment of profound learning and growth – so employees can thrive in all areas of their lives, in and outside of work. Ultimately, we want to be an organization where we would be proud for our family, friends and children to work.

If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team.

Position Summary:

ultraimpact – Make a difference for those who need it most

Ultragenyx is seeking an accomplished medical affairs leader, motivated by working in a highly scientific, innovative, and fast-paced environment, and driven to lead the future of rare disease medicine. This exceptional leader must have deep scientific knowledge, strong business acumen, and exemplary communication skills. The Senior Director will play a key medical leadership role in the LC-FAOD and MPS franchises for the US region, supporting assets with distinct lifecycle management cycles.

Work Model:

Remote: Officially documented as working full-time from home, with travel to Ultragenyx's offices or other locations on occasion as needed.

Responsibilities:

Serve as the medical lead for LC-FAOD, MPS VII and MPS IIIA, accountable for the regional pull-through of the global medical strategy, and the development and timely execution of US tactical plans aligned to brand strategy and lifecycle priorities

Serve as the UX111 US medical launch team, accountable for developing and leading the execution of a robust medical launch plan, partnering closely with the Field Medical and Gene Therapy Treatment Teams. Provide clear directions to teams to ensure successful execution of the launch plan

Accountable to define and deliver meaningful strategic goals that demonstrate measurable impact on medical affairs and business outcomes
Lead and/or implement US data generation activities aligned to the integrated evidence plan/US medical needs and provide medical leadership for associated evidence dissemination activities
Build and maintain strong relationships with key opinion leaders (KOLs); integrate insights into strategic planning and lead collaborations on priority initiatives, such as advisory boards, QTC connect meetings and payer education as needed
Provide deep disease area and product expertise, ensuring accurate and consistent communication of clinical and scientific data
Lead US conference strategy, including the delivery of scientific education symposia and other educational events that advance HCP knowledge and understanding of assigned programs
Collaborate closely with the US field medical team, supporting the full cycle of strategic insights generation through to action
Ensure development of impactful scientific resources (slide decks, FAQs, educational materi