Principal Scientist - Inflammation Biomarkers

Career Category

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Principal Scientist - Inflammation Biomarkers

What you will do

Let’s do this. Let’s change the world. In this vital role you will help drive scientific and technical plans collaboratively with other members of the Precision Medicine function, as well as with members of the Amgen research and development community. You will successfully partner with cross-functional stakeholders to drive clinical biomarker innovation for clinical-stage assets in inflammatory diseases. The Principal Scientist will possess biomarker expertise in inflammatory and/or rare diseases such as arthritis, atopic dermatitis, inflammatory bowel disease, lupus, asthma, and/or autoimmune endocrinopathies.

Key Responsibilities:

• Preparing clinical biomarker strategies, leading biomarker development, implementation, and execution for one or more programs
• Responsible for biomarker elements in clinical protocols, biomarker analysis plans, regulatory submissions, investigator meetings, advisory boards and publications
• Build productive relationships with team members and functional groups for integrating an aligned and prioritized clinical biomarker evidence plan that addresses clinical objectives and translational research
• Partner with cross-functional stakeholders including to drive biomarker innovation at product level
• Establish and implement biomarker studies and collaborations with academic laboratories/KOLs
• Interpret and communicate key clinical biomarker findings to cross-functional teams including Precision Medicine teams and leadership
• Responsible for robust clinical biomarker plans to deliver patient stratification/selection, pharmacodynamics, mechanism of action and resistance evidence from clinical trial samples

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications:

Doctorate degree in a bioscience or medical discipline and 2 years of industry experience

Or

Master’s degree in a bioscience or medical discipline and 4 years of industry experience

Or

Bachelor’s degree in a bioscience or medical discipline and 6 years of industry experience

Or

Associate’s degree in a bioscience or medical discipline and 10 years of industry experience

Or

High school diploma / GED and 12 years of directly related industry experience

Preferred Qualifications:

• PhD with 3 or more years pharmaceutical industry experience, developing biomarker strategies in a clinical development setting and/or in preclinical biomarker discovery/validation
• Knowledge and translational biomarker experience in inflammation is highly desirable
• Strong background in immunology, cell biology and genomics
• Clinical development experience working with cross-functional teams conducting clinical trials
• Experience in developing program-based strategies for pharmacodynamic, predictive, and exploratory biomarkers
• Experience implementing a broad array of biomarker platforms and technologies to support clinical-stage programs
• Demonstrated ability to establish and implement biomarker studies and collaborations with academic laboratories/KOLs
• Experience in assay development and qualification and analysis of clinical samples
• Experience managing biomarker assay outsourcing processes with external vendors and CROs
• Poise and professionalism with strong communication and influencing skills in a dynamic environment

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to