Senior Associate Scientist- Formulations

Use Your Power for Purpose

Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. At the core of this mission is Research and Development, where we strive to transform advanced science and technologies into the most impactful therapies and vaccines. Whether you are involved in discovery sciences, ensuring drug safety and efficacy, or supporting clinical trials, you will leverage cutting-edge design and process development capabilities. This collaborative effort accelerates the delivery of best-in-class medicines to patients globally, fulfilling Pfizer’s commitment to making a significant difference in healthcare.

What You Will Achieve

In this role, you will be part of Pharmaceutical Research and Development, supporting Pfizer’s biotherapeutics portfolio, which includes peptides, proteins, monoclonal antibodies (mAbs), antibody–drug conjugates (ADCs), vaccines, mRNA, and other biologics. You will contribute to the development of parenteral formulations across these modalities.

The position involves performing formulation development and analytical characterization of candidate molecules using a range of biophysical and biochemical techniques. You will also support drug product manufacturing process development and be responsible for data compilation, presentations, and technical report writing.

A strong foundation in scientific principles and best practices will enable you to meet critical deadlines and deliver high‑quality work. As a technical contributor, you will assess assigned tasks and make informed decisions through the direct application of your expertise. Your dedication will help Pfizer reach new milestones and ultimately improve the lives of patients worldwide.

How You Will Achieve It

The responsibilities of the Senior Associate Scientist position include, but are not limited to:

• Participate in the development of parenteral formulations for biotherapeutic modalities, including peptide‑based therapeutics, mAbs, ADCs, proteins, and vaccines. Under general supervision, support the development of associated drug product manufacturing processes.

• Perform rapid and comprehensive characterization of candidate molecules to establish stability profiles and apply these insights to develop appropriate dosage forms that meet clinical requirements. This work will utilize a broad range of biophysical and biochemical techniques, including UPLC (SE‑UPLC, IEX, RP‑UPLC), SDS‑PAGE, LC‑MS, capillary gel electrophoresis (CGE), imaged capillary electrophoresis (iCE), and spectroscopy methods such as UV, fluorescence, circular dichroism, and FTIR.

• Assist in the development and scale‑up of drug product processes from bench‑top to pilot scale, and, as required, support technology transfer to commercial manufacturing facilities. Drug product processes may include fluid handling, sterilizing filtration, and lyophilization.

• Collaborate effectively with a multidisciplinary team of scientists to support formulation optimization and overall candidate progression.

• Prepare data summary presentations, compile experimental data, and author technical reports to clearly communicate results and conclusions.

• Demonstrate effective communication skills when interacting with laboratory scientists, project managers, and cross‑functional colleagues while contributing to multidisciplinary project teams.

Here Is What You Need (Minimum Requirements)

• Bachelor’s degree (BA/BS) in Biochemistry, Chemical or Biochemical Engineering, Pharmacy, Chemistry, Biology, or a related discipline with 2–4 years of relevant experience, or a Master’s degree with 0–2 years of experience.

• Hands‑on laboratory experience with a variety of analytical techniques.

• Experience with analytical characterization of biotherapeutics using techniques such as UPLC (IEX), SDS‑PAGE, capillary gel electrophoresis (CGE), imaged capillary electrophoresis (iCE), and spectroscopic methods.

• Strong organizational and time‑management skills.

• Excellent oral and written communication skills.

• Proficiency with general computer software, including word processing, spreadsheets, and presentation tools.

• Demonstrated ability to solve scientific problems using contemporary experimental techniques.

• Experience accurately recording experimental details and data in an electronic laboratory notebook (ELN).

Bonus Points If You Have (Preferred Requirements)

• Master’s degree in a relevant scientific discipline.

• Experience in peptide synthesis, or peptide conjugation (including lipidated and/or chemically modified peptides), formulation development, or an