Senior Scientist

Our purpose is to bring hope to life by enabling life-changing therapies for patients around the globe, creating a healthier and happier tomorrow. Our mission is to work side by side with our customers in order to improve patients’ lives by bringing new biopharmaceuticals to market.

AGC is looking for a Senior Scientist for Analytical Method Development, Bioassay. We are seeking a profile with expertise in analysis of protein-based biotherapeutics within CMC, by methods such as Cell-based assays, ELISA, Octet and qPCR.

AGC Biologics A/S is an international Contract Development and Manufacturing Organization with facilities in Denmark, Germany, Italy, Japan and USA and with clients all over the world. The position will be anchored in the Bioassay team in the Analytical Method Development (AMD) Department at the Copenhagen site of AGC (located in Søborg).
 

The Department
The AMD Department consists of 26 dedicated and highly competent scientists and technicians working in two sub-teams: Characterization & HPLC and Bioassay.

AMD is responsible for:

• Transfer-in, development and optimization of analytical procedures

• Transfer of analytical methods to QC for validation

• Analytical support to early-stage and late-stage process development departments

• Characterization of biotherapeutic products and drug intermediates

• Implementation of new analytical technologies and techniques, including automation

AGC projects range from early-stage pre-clinical development through all phases of clinical development to commercial supply. AMD is involved in cross-functional project groups and is in close contact with our counterparts in Seattle (USA), Boulder (USA), Heidelberg (GER) and Chiba (JPN) facilities.


As a scientist in AMD, you will be involved in a wide range of exciting tasks and challenges. You will be responsible for implementing, developing and optimizing bioassays for a wide range of protein-based therapeutics, using different techniques (e.g. ELISA, Octet, Cell-based assays, qPCR, spectrophotometry). You will work in close collaboration with colleagues in AMD and with our external clients, where you will be responsible for the analytical package for one or more projects. - All in the quest to support our clients in getting a high-quality product to the market as fast as possible.
 

You will be working within a team of 4 scientists and 6 technicians. Furthermore, you will collaborate with multiple stakeholders including process development, project managers and QC.

The work environment in our department is very informal. There is constant collaboration across the organization, and all employees have a professional and flexible attitude towards their work. We can promise an exciting and diverse job.


Responsibilities And Tasks
You will get the opportunity to work with colleagues and clients with different backgrounds and personalities and you will be exposed to a diverse set of drug products in different clinical stages. You will get the opportunity to use and develop your professional and personal skills in a cross-functional and very interactive environment.


The Job Includes

• Transfer-in, development and optimization of analytical methods for protein-based biopharmaceuticals. On a daily basis, you will be designing experiments and evaluating data.

• Evaluating methods received from clients before method transfer to AGC.

• Ensuring method suitability for use in QC through extensive testing.

• Troubleshooting of analytical methods and instruments.

• Representation of AMD in cross-functional CMC project teams with responsibility for the analytical package.

• Verbal and written reporting to clients.
   

Experience And Competencies
The ideal candidate has a higher educational background in Protein Chemistry, Biochemistry, Pharmaceutical Sciences, Biochemical or Chemical engineering, or related scientific background (MSc or PhD), preferably with 3+ years of experience in analytics from the biotech or pharma industry. In addition to this you have:

• Experience with executing implementation of bioassays within CMC.

• Experience with handling and analyzing biopharmaceuticals.

• Understanding of biopharmaceutical manufacturing and regulatory requirements.

• Experience with and understanding of analytical instrumentation, e.g. Octet, SoloVPE, qPCR instruments, liquid handlers etc.

• Ability to work independently in a dynamic environment.

• Good communication skills and you thrive in a departme