Sr Principal Scientist/Global Biomarker Lead – Oncology Clinical Biomarkers

Career Category

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Sr Principal Scientist/Global Biomarker Lead – Oncology Clinical Biomarkers

What you will do

Let’s do this. Let’s change the world. The Senior Principal Scientist at Amgen is a leading expert responsible for planning and executing biomarker research within oncology clinical studies. Their work, using advanced technologies and methodologies, helps in the translation and clinical development of the company's products.

In this vital role you will successfully partner with cross-functional stakeholders to drive clinical biomarker innovation for oncology clinical assets.

• Responsible for preparing clinical biomarker strategies, leading biomarker development, implementation, and execution for one or more programs
• Responsible for robust clinical biomarker plans to deliver patient stratification/selection, pharmacodynamics, mechanism of action and resistance evidence from clinical trial samples
• Responsible for biomarker elements in clinical protocols, biomarker analysis plans, regulatory submissions, investigator meetings, advisory boards and publications
• Build productive relationships with team members and functional groups for integrating an aligned and prioritized clinical biomarker evidence plan that addresses clinical objectives and translational research
• Partners with cross functional stakeholders including to drive biomarker innovation at product level
• Interprets and communicates key clinical biomarker findings to cross functional teams including Precision Medicine teams and leadership

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications:

Doctorate degree and 2 years of industry experience in oncology clinical biomarker development

Or

Master’s degree and 4 years of industry experience in oncology clinical biomarker development

Or

Bachelor’s degree and 6 years of industry experience in oncology clinical biomarker development

Or

Associate’s degree and 10 years of industry experience in oncology clinical biomarker development

Or

High school diploma / GED and 12 years of industry experience in oncology clinical biomarker development

Preferred Qualifications:

• Doctorate degree (PhD and/or MD) with 5+ years industry experience developing oncology biomarker strategies in a clinical development setting
• Experience developing and executing pharmacodynamic, predictive and exploratory biomarkers such as mechanisms of resistance with clinical trial samples
• Experience implementing a broad array of biomarker platforms and technologies to support oncology clinical programs
• Clinical development experience working with cross-functional teams conducting clinical trials
• Demonstrated ability to establish and implement biomarker studies and collaborations with academic laboratories/KOLs as well as CROs
• Knowledge of biomarker assay development and qualification, analysis of clinical samples, and leading biomarker assay outsourcing processes with external vendors and CROs
• Experience working effectively in a team environment with cross-cultural partners
• Strong written and verbal communication skills with experience drafting technical reports and biomarker publications, and interpreting and communicating biomarker results to cross-functional teams

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U