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Manager, Accounting Operations

Arvinas
New Haven, United StatesRemotefull_timeVerifiedPosted 9 Oct 2025

About the role

Arvinas is a clinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins. Arvinas uses its proprietary PROTAC® Discovery Engine platform to engineer proteolysis targeting chimeras, or PROTAC® targeted protein degraders, that are designed to harness the body’s own natural protein disposal system to selectively and efficiently degrade and remove disease-causing proteins.

In addition to its robust preclinical pipeline of PROTAC protein degraders against validated and “undruggable” targets, the company has three investigational clinical-stage programs currently enrolling: vepdegestrant for the treatment of patients with locally advanced or metastatic ER+/HER2- breast cancer; ARV-102 for the treatment of patients with neurodegenerative disorders, and ARV-393 for the treatment of patients with relapsed/refractory non-Hodgkin Lymphoma and potentially other lymphomas.

In April 2024, Arvinas entered into a transaction with Novartis, including a global license agreement for the development and commercialization of the clinical stage PROTAC® androgen receptor protein degrader ARV-766 for the treatment of prostate cancer. The transaction closed in May 2024.

#TeamArvinas is made up of passionate and curious employees, whose diverse thoughts and perspectives are highly valued. Arvinas employees embrace the freedom to pursue innovation, think creatively, and give back. They are driven by the company’s values and mission – to improve the lives of patients with serious diseases by pioneering therapies created with our revolutionary PROTAC® protein degradation platform. We’re really excited about the work we’re doing inside and outside of Arvinas, and think you will be, too. But don’t just take our word for it – learn more about life at Arvinas and what employees have to say.

For more information, please visit www.arvinas.com

Position Summary

We are seeking a detail-oriented and strategic Manager of Accounting Operations to lead our accounting and accounts payable operations. This leadership role requires deep accounting knowledge, strong managerial skills, and the ability to drive cross-functional collaboration across finance, procurement, and operations.

This position reports to the Senior Director of Financial Operations and Accounting and can be remote, hybrid, or located at our headquarters in New Haven, CT.

Principal Responsibilities

Key responsibilities of this role include, but are not limited to:

  • Manage the monthly, quarterly, and annual financial close processes, ensuring timely and accurate reporting.
  • Prepare and review journal entries, accruals and account reconciliations.
  • Own day-to-day accounting operations, including maintenance of the general ledger, accounts payable/receivable, fixed asset management, journal entries, and account reconciliations.
  • Lead, mentor and develop accounting and accounts payable staff to drive performance and professional growth.
  • Provide leadership, direction, and oversight to the accounts payable team responsible for invoice processing, vendor maintenance, and payment execution.
  • Ensure compliance with GAAP, internal policies, and all applicable regulatory requirements.
  • Collaborate with procurement, operations, and legal teams to ensure procure to pay processes are efficient, well-documented, and aligned with internal controls.
  • Monitor key metrics related to month-end close cycle timeline, general ledger accuracy, accounts payable turnover, etc.
  • Partner with FP&A for budgeting, forecasting, and financial analysis.
  • Support internal and external audit efforts.
  • Drive continuous improvement initiations and process enhancements to systems and month-end close processes, embracing digital automation.
  • Assist in the implementation of

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Company

Arvinas

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