Jobs and Careers

Senior Manager, SOX & Technical Accounting

South San Francisco, United Statesfull_timeVerifiedPosted 3 Aug 2026

💰 $210,000/yr($170,000/yr – $210,000/yr)

About the role

About Us

Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world.

It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve.

Led by Tassos Gianakakos, Jay Edelberg, M.D., Ph.D., and Bob McDowell, Ph.D., Kardigan’s co-founders have reunited after leading MyoKardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020.

We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients.

At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals. Driven by patients and their families, we are deeply committed to improving the lives of patients and prioritizing their needs above all else. We believe in being authentic—leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an eagerness to learn, we encourage the highest levels of curiosity and are open to changing our minds. We are committed to winning as a team with urgency, excellence, and intention, and support each other no matter what role we play or where we sit. Lastly, we strive to enable the impossible because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries.

These values are the foundation of our work, empowering us to make a real difference, every day.

Position Title: Senior Manager, SOX & Technical Accounting

Department: Accounting

Reports To: Director, SEC & Technical Accounting

Location: Princeton, NJ – On-site 4 days per week (Mon to Thurs)

Job Overview

Kardigan is seeking an experienced and detail-driven Senior Manager, SOX & Technical Accounting to play a critical role in supporting the company’s accounting and compliance functions as we continue to scale as a public company. This role will lead the Company’s SOX compliance program while also serving as a key resource for technical and operational accounting matters, including stock-based compensation, lease accounting, and other complex accounting areas.

The Senior Manager, SOX & Technical Accounting will partner closely with the Accounting & Finance leadership, external auditors, and cross-functional stakeholders to ensure effective internal controls, compliance with accounting standards, and accurate financial reporting. This position requires a strong foundation in SOX compliance, technical accounting, operational accounting, and process improvement, as well as a deep understanding of the biopharmaceutical or biotechnology industry. A demonstrated interest in leveraging technology, automation, and emerging AI tools to enhance accounting processes, controls, and reporting is strongly preferred.

Essential Duties and Responsibilities

SOX Compliance & Internal Controls:
Lead and manage all aspects of the company’s SOX compliance program, including annual risk assessments, process documentation, control design, walkthroughs, testing coordination, remediation efforts, and ongoing monitoring. Partner with process owners across the organization to maintain and strengthen an effective internal control environment and support compliance with Sarbanes-Oxley requirements.

Technical & Operational Accounting:
Serve as the subject matter expert on technical and operational accounting matters, including stock-based compensation, lease accounting, equity transactions, and other complex accounting areas. Research accounting implications of new transactions, prepare technical accounting memos, and ensure compliance with U.S. GAAP and company policies.

Financial Reporting & Compliance:
Support the preparation of quarterly and annual financial statements and disclosures. Partner with the