Director, Medical Information and Scientific Communications

Attention recruitment agencies: All agency inquiries are vetted through 4DMT’s internal Talent Acquisition team. No unsolicited resumes will be accepted. The 4DMT Talent Acquisition team must expressly engage agencies on any requisition. Agencies contacting hiring managers directly will not be tolerated, and doing so may impact your ability to work with 4DMT in the future.

 

4DMT is a clinical-stage biotherapeutics company harnessing the power of directed evolution for targeted genetic medicines. We seek to unlock the full potential of gene therapy using our platform, Therapeutic Vector Evolution (TVE), which combines the power of directed evolution with our approximately one billion synthetic AAV capsid-derived sequences to invent evolved vectors for use in our products. We believe key features of our targeted and evolved vectors will help us create targeted product candidates with improved therapeutic profiles. These profiles will allow us to treat a broad range of large market diseases, unlike most current genetic medicines that generally focus on rare or small market diseases.  

Company Differentiators: 

•    Fully integrated clinical-phase company with internal manufacturing
•    Demonstrated ability to move rapidly from idea to IND
•    Five candidate products in the clinic and two declared pre-clinical programs
•    Robust technology and IP foundation, including our TVE and manufacturing platforms
•    Initial product safety and efficacy data substantiates the value of our platforms
•    Opportunities to expand to other indications and modalities within genetic medicine

GENERAL SUMMARY 

The Director, Medical Information and Scientific Communications will shape the global scientific communications strategy and across 4DMT’s therapeutic asset portfolio and collaborate with internal and external stakeholders to accomplish the timely dissemination of data and scientific messages via peer-reviewed journal articles, congress abstracts, scientific presentations and all other suitable forums. This role will also implement standard response letters and FAQs to support all portfolio assets, in alignment with existing data and key messages. This role will collaborate with clinical development, clinical development operations, external engagement, biometrics, data management, regulatory affairs, drug safety, commercial, and alliance partners. 

Reporting to the VP, Medical Affairs, this individual contributor role will serve as a subject matter expert to internal and external stakeholders. Depending on location, this role may be fully remote or hybrid. 

*Direct experience in scientific communications as an employee of a pharma/biotech company is required as well as strong Phase III communications support and launch preparedness. 

 

RESPONSIBILITIES: 

• Lead the annual development and implementation of comprehensive asset-specific scientific publication plans mapped to core scientific statements and key open questions. 

• Develop a standard lexicon and evidence-based core scientific statements to ensure clarity, accuracy, and consistency of language and messages across multiple platforms 

• Analyze and interpret data and draft original research manuscripts, review articles, congress abstracts, and scientific presentations 

• Collaborate with internal and external stakeholders to ensure timely delivery of manuscripts, abstracts, and congress presentations based on company-sponsored discovery, preclinical research, and clinical research 

• Collect and adjudicate comments from all publication authors 

• Train and rehearse podium speakers as needed 

• Create and support data presentations for investor relations activities as required 

• Achieve subject matter expertise in the relevant therapeutic areas 

• Foster and maintain collaborative relationships with academic and clinical experts, publishers, and medical associations 

• Adhere to standard operating procedures for the preparation and cross-functional review of scientific manuscripts, abstracts, and congress presentations 

• Ensure compliance with good publication practice standards and guidelines (e.g., Good Publication Practice 3 Guidelines; ICMJE Recommendations for the Conduct, Reporting, Editing