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Senior Staff Scientist

Baylor College of Medicine
United Statesfull_timeVerifiedPosted 17 Feb 2026

About the role

Summary

The Buffington lab is looking for an individual with a background in biochemistry and cellular biology to contribute to ongoing projects. The Senior Staff Scientist will establish novel biochemical assays to study protein-protein interactions and the ensuing dynamic and structural changes in protein conformations resulting from the interactions per se or the regulatory post-translational modifications that might occur on these proteins. This project is ideal for individuals who will lead projects in the laboratory without the responsibilities of running the lab or writing grants.

Job Duties

  • Responsible for the evaluation, selection and application of advanced laboratory techniques, such as whole cell patch clamp electrophysiology techniques, quantitative analysis of acquired data, and the generation of representative traces
  • Plan, direct and conduct research experiments
  • Perform ex vivo slice electrophysiology
  • Record local field potentials and from single cells in brain slices or cultured primary neurons
  • Perform in vivo awake behaving animal recordings
  • Conduct literature searches and summarizes information in an appropriate format for a particular study with the intent of developing expertise in in vivo recordings, calcium imaging, and fiber photometry
  • Troubleshoot and provide solutions to improve outcomes and experiment design
  • Document results of experiments and reports to principal investigator
  • Train and supervise less experienced research staff
  • Oversee the maintenance of lab equipment and environment
  • Perform other job related duties as assigned

Minimum Qualifications

  • Doctoral Degree. Experience may not be substituted in lieu of degree.
  • Seven years of postdoctoral research experience.

Department Specific Criteria

  • Experience with ex vivo slice electrophysiology
  • Experience with animal models, recordings in vivo awake behaving animals
  • Neuroscience experience

Preferred Qualifications

  • Doctoral Degree in Biochemistry, Molecular Biology or other Biomedical Sciences.
  • Evidence of scientific writing is a plus.

 

 

 

Work Authorization Requirement:

This position is not eligible for visa sponsorship. Candidates must be legally authorized to work in the United States at the time of application and throughout the duration of employment. 

 

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

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Company

Baylor College of Medicine

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