Job Description

Background and General Summary:

Vertex Pharmaceuticals operates at the forefront of scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), Casgevy, a gene therapy for sickle cell disease and beta-thalassemia and Journavx, a novel new treatment for moderate to severe acute pain. Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in kidney diseases, Type 1 diabetes, among others.

As Vertex grows in scale and complexity, it is establishing a new center of excellence—the Global Pricing & Analytics Group (GPAG)—to build industry-leading capabilities in global pricing analytics. GPAG will evaluate pricing strategies, measure performance, and deliver actionable insights across regions and the portfolio. Vertex is seeking a Senior Director based in Boston, MA, to lead this new function within the current Global Value & Access Strategy (GVAS) team. This role reports to the VP of GVAS and will serve on the GVAS Leadership Team.

The Head of GPAG will help shape the group’s long-term vision and develop a five-year roadmap for priority technology and pricing capabilities, define the target future state, identify gaps and the resources required to deliver change. The successful candidate will demonstrate strong cross-functional leadership, thrive in a complex environment, and bring a problem-solving mindset grounded in strong analytical skills. As a senior member of the GVAS team, this individual must model Vertex’s ethics and culture and be committed to developing the next generation of leaders.

 Key Responsibilities: 

• Lead development of a Global Pricing Analytics capability to sustain value optimization for the Vertex portfolio
  • Assess the current Global pricing data infrastructure and provide recommendations for future requirements
  • Develop a set of Global Pricing Analytics deliverables to guide decision-making and performance assessments across Vertex disease areas and Regions
  • Build a Global Pricing Analytics reporting infrastructure that integrates multiple data sources and automates insight delivery, including realized prices
• Serve as the Global Value & Access Strategy subject matter expert on Advanced Analytics, including appropriate integration of Artificial Intelligence pilots, capabilities and training for GVAS
• Oversee operations for Global Price Governance including continual updating of guidance documents to audit standards, templates and Regional training
  • Ensure compliance with Global Price Policies in partnership with GVAS Disease Area Leads, and manage the annual review process for Global price floors
  • Develop disease specific performance analytics analyzing negotiation outcomes and achievement of business results relative to pre-deal analysis
• Lead pricing capability development as required including elements of lifecycle pricing, launch sequencing and risk assessment in close cooperation with relevant stakeholders
• Lead development of systematic P&MA global horizon scanning and internal knowledge management to increase team efficiency and effectiveness of external insights 
• Partner with key stakeholders, including US and International Market Access, Global Value & Access Strategy, Global Commercial Strategy, Finance, and DTE to support the development of key GPAG deliverables

 Experience & Qualifications: 

• Bachelor’s degree required, ideally in life sciences, post graduate preferred
• 12+ years of direct biotechnology / pharmaceutical industry experience; 5+ years of supervisory / management experience preferred
• Working knowledge of US and/or ex-US pricing environment is required
• Strong practical, quantitative and analytical skills combined with a sound understanding of how to successfully apply pricing & reimbursement principles to support Vertex
• Excellent working knowledge of US and International Market Access data sets including MMIT, IQVIA, Pricing / GTN (Model-N), and Real-World Data (DRG, Market Scan, etc.).
• Experience creating and/or supporting complex analytics and working closely with data scientists
• Strong proficiency in Tableau and/or Power BI, along with working knowledge of data lake platforms such as Snowflake is a plus.
• Exhibits outstanding written and oral communication skills, including the ability to effectively write and deliver presentations to professionals at all levels within Vertex
• Demonstrated ability to manage initiatives that require cross-functional collaboration and relationships at all levels of the organization and across geographies
• General experience in commercialization and drug developm