Global Clinical Head, Immunology Cell Therapy

Job Profile: Global Clinical Head, Immunology Cell Therapy

Location: Office-based role in Boston Seaport MA

Are you a visionary leader in clinical drug development, possessing the capabilities to drive a successful strategy in accelerating the development of cellular therapies for patients with immune-mediated diseases? Are you dedicated to revolutionizing the treatment of immune-mediated diseases and significantly impacting patients' lives? Do you have a strong passion for science and meaningful clinical development experience in Immunology and CAR-T cell therapies? Do you possess both strategic and operational leadership skills? If so, we invite you to join us! We are seeking a Global Clinical Head, Immunology Cell Therapy based in Boston Seaport.

About AstraZeneca

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. We are more than one of the world’s leading pharmaceutical companies.

Immunology Cell Therapy

Our ambition is to build a world-class organization that accelerates the delivery of ground-breaking cell therapies for patients with immune-mediated diseases. It’s our big vision that unites and inspires us. Cell therapies represent a fundamental evolution of how drugs are discovered, developed and manufactured, these new advanced potentially curative cellular modalities require a new development strategy to ensure their rapid availability to patients. With multiple autoimmune and inflammatory indications and clinical-stage cell therapies in global development, we keep pushing forward, focusing on ground breaking science with the latest technology to achieve breakthroughs.   AZ is a place built on courage, curiosity and teamwork – we make bold decisions driven by patient outcomes.

What You’ll Do

The Global Clinical Head for Immunology Cell Therapy holds a senior leadership position within a new and dynamic organization at AstraZeneca. This is an exceptionally exciting and prestigious role, contributing significantly to AstraZeneca's global objectives and the value targets of our portfolio. Reporting directly to the Head of Immunology Cell Therapy in Boston, this individual will also be a pivotal member of the leadership team. As the Global clinical head, they are responsible for spearheading the program and related studies in immune-mediated diseases. The GCH is the most senior medical scientific expert on an asset/product/indication team and is a core member of the Franchise Team (if applicable) and/or the Global Product Teams (GPT). Moreover, this role offers the outstanding opportunity to collaborate closely with cross-functional teams at the enterprise level, including Oncology, Alexion, and several development partners, thereby improving the overall impact and reach of the position.

Responsibilities:

• Provide expert clinical and medical expertise input into overall cell therapy programs and portfolio strategies.

• Accountable for all clinical scientific aspects of the product/asset, including the benefit/risk of a product and/or asset as well as the scientific strategies for clinical components of the Target Product Profile (TPP), Target Product Claim (TPC), Clinical Development Plan (CDP), Clinical components of regulatory documents and core labelling texts.

• Single point accountable leader for the design, delivery and interpretation of clinical studies ensuring the ethical and scientific integrity of the plans, studies and the products in compliance with GCP

• Provide impactful medical strategy and cell therapy expertise to Research, Translational Medicine, Early and Late-stage Clinical Development and Commercial Partners, including in the development of therapeutic area strategy

• Closely follow medical developments within assigned areas, including cell therapy for autoimmune/inflammatory diseases, and disseminate new information within Clinical Development and wider organization, to transform trends and emerging data into agile clinical plans

• Work closely and collaborate across early and late clinical development, partner functions and wider AZ organization in Oncology and rare disease to ensure the design and delivery of clinical development plans with high quality and speed

Essential Qualifications Required for this Role

• M.B.B.S. or M.D. degree, MD/PhD with specialty or experience in the Immunology therapeutic area and CAR-T cell therapies

• Postgraduate subspecialty training medical training in a relevant field with a history of holding