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Senior Research Investigator (Department of Hematology/Oncology)

University of Pennsylvania Perelman School of Medicine
Medical School-Johnson Pavilion, United States, United Statesfull_timeVerifiedPosted 2 Feb 2026
💰 $99,289/yr($79,500/yr$99,289/yr)

About the role

University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning. As an employer Penn has been ranked nationally on many occasions with the most recent award from Forbes who named Penn one of America’s Best Large Employers in 2023.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Posted Job Title

Senior Research Investigator (Department of Hematology/Oncology)

Job Profile Title

Research Investigator, Senior

Job Description Summary

The Shaw-Hahn laboratory pursues basic and translational research on global pathogens including HIV and hepatitis C virus (HCV). For HIV, the laboratory makes extensive use of the simian-human immunodeficiency virus (SHIV) model of infection in Indian rhesus macaque monkeys. This requires that the successful applicant to have a high level of scientific knowledge and understanding of RNA viruses and complex biological and immunological systems. This individual must have extensive experience working with BSL2/3 pathogens. It is expected that this position will lead basic and translational research projects supporting the overall mission of the laboratory. A PhD, is required along with at least 5 years of post doctoral experience working with HIV, SIV, SHIV, HCV or related pathogens.

Job Description

Job Responsibilities

  • DNA sequencing and analysis

  • Broadly neutralizing monoclonal antibody isolation and characterization

  • Single genome amplification and analysis

  • Molecular characterization of Env-Ab coevolution leading to neutralization breadth

  • mRNA and protein trimer HIV-1 immunogen design

  • Conduct of preclinical vaccination studies in Indian rhesus macaques

  • Perform data analysis and other aspects of quantitative and qualitative research as well as theoretical research

  • Other duties and responsibilities as assigned

Qualifications

  • Doctor of Medicine, Doctor of Philosophy, and 5 to 7 years of postdoctoral experience is required.

Contingent upon funding.

Job Location - City, State

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine

Pay Range

$79,500.00 - $99,289.00 Annual Rate

Salary offers are made based on the can

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