Global Head, Health Economics and Outcomes Research (HEOR)

Kyowa Kirin is a fast growing global specialty pharmaceutical company that applies state-of-the-art biotechnologies to discover and deliver novel medicines in four areas of unmet need: oncology, nephrology, immunology and CNS/movement disorders. The North America organization includes three offices (in New Jersey and California) that focus on drug discovery, product development, and commercialization. Together, we work as a close-knit team to understand clinical needs and advance innovations that can have a profound impact on patient lives.

As a patient centric organization that strives to deliver innovative medicines to meet unmet needs, we feel that it is critical to follow the safety guidelines defined by CDC and OSHA. We believe the COVID-19 vaccine is the best way to manage COVID risk to you, your colleagues, your family and our society. With that in mind, we are taking the essential step to ensure the safety of our employees during this health crisis by requiring all US employees, temporary workers, agency employees and independent contractors to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. In accordance with applicable law, individuals may seek an accommodation for medical or disability-related conditions or sincerely held religious beliefs.

Job Purpose:

The purpose of the role is to drive the demonstration of value for Kyowa Kirin’s (KK) current and future portfolio, optimizing the demonstration of patient benefit and achieving access, with a strong focus on Outcomes Research (OR), (for example Patient-reported Outcomes (PROs), Clinician-reported Outcomes, Performance Outcomes and Observer-Reported Outcomes), Health Economics (HE) and Real-World Data (RWD) sources and Real-World Evidence (RWE). The Global HEOR Head is responsible for developing global HEOR strategies of current and future portfolio of products in collaboration with Global Medical Affairs Therapeutic Area (TA) Heads. The incumbent is also responsible for building capability in the HEOR function in KK to deliver compelling evidence for current and future products.

Key responsibilities:

• Lead global HEOR strategies of KK products, in alignment with the integrated evidence generation plans lead by the global TA heads.
• Assess the global value evidence requirements of the KK pipeline products through cross-functional stakeholder insights and, in alignment with the global TA heads, contribute to prioritizing evidence gaps, and contribute to developing and implementing HEOR/RWE plans to address these data gaps.
• In alignment with the global TA heads, manage and implement key HEOR aspects of evidence generation strategies to support KK pipeline products and inform the target product profile (TPP), including early health economic modelling, PROs, burden/cost of illness and innovative retrospective and prospective RWE studies.
• Collaborate closely with global matrix disciplines such as Clinical Development, Regulatory, Market Access, Commercial Leads and Global Medical Affairs (in particular the TA heads) to influence and ensure integration of strategy and health outcomes studies/data to support internal decision-making during product development, commercialization and throughout life cycle management of the asset.
• Ensure that the patient’s voice is included in product development and demonstration of unmet need utilizing public and patient involvement as appropriate for selection, development and validation of global PRO/clinical outcome assessment (COA) endpoint strategies to support registration, reimbursement and differentiation of KK products.
• Ensure the development, delivery and support for robust health economic models to support market access submissions globally, providing support for all country economic submissions.
• Lead planning of global communication and dissemination of new HEOR data through effective publication planning in collaboration with Global Medical Therapeutic Area/Product Head.
• Project and vendor management. Track and adjust global HEOR projects across team and with external contractors and suppliers to ensure delivery on time, to budget and in accordance with user specifications.
• Collaborate with senior stakeholders through appropriate company processes in ensuring quality of deliverables, including review and sign-off of project specifications, protocols, data analysis plans, final study reports, publications.
• Provide review via Global Medical Affairs Committee and support Regions/Affiliates to ensure local HEOR plans and data is of high quality and will meet evidence needs.
• Be the “go to” person on all matters related to HEOR, building a high-quality function to deliver innovative approaches to meet the needs of stakeholders today and in the fut