Senior Principal Software Engineer

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us. 

About Lilly  

At Lilly, everything we do starts with patients. We unite caring with discovery to make life better for people around the world. Headquartered in Indianapolis, Indiana, our global team of over 50,000 employees work with urgency and purpose to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. We bring our best to this work because people depend on it. If you’re driven by purpose and determined to make a meaningful difference for patients, we invite you to bring your skill and your commitment to Lilly.  
 

About Technology@Lilly  

At Lilly, technology is not a support function. It is how a global medicine company operates, innovates, and delivers. Lilly in Hyderabad builds the capabilities that make this possible, cloud platforms, AI systems, and automation at enterprise scale, all in service of a purpose that makes this technology work genuinely distinctive, from advancing drug discovery to enabling connected clinical trials to keeping a global medicine company running at the standard patients deserve.
 

About the Business Function  

The Software Product Engineering (SPE) team is a specialized engineering group that delivers strategic solutions and differentiated capabilities. We take a forward-thinking approach, focusing on an enterprise platform and product mindset, ensuring that the solutions we build can be leveraged across Technology teams for broader impact and efficiency.  

About the Role - Senior Principal Software Engineer ​

We are looking for a passionate and driven Software Engineer to join our Software Product Engineering team. In this role, you will design, build, and scale intelligent systems that leverage the latest advances in Generative AI and Large Language Models. You will work closely with product, data science, and infrastructure teams to deliver robust, production-grade solutions that power real-world use cases across the organization. You should be comfortable working across the stack, from crafting clean backend services to contributing to frontend experiences and be excited about the rapidly evolving landscape of agentic AI, model-context protocols, and cloud-native architecture.  
 

Why You Should Be Interested in This Role

This is not a typical Software Engineering role.

• Autonomous team. We move fast, iterate, and solve real problems for real customers.

• AI-first from day one. You are curious, learn quickly, empathize with our users, and build solutions to critical problems that shape how Lilly operates.

• Full SDLC ownership. Every engineer moves across ideation, build, QA, deployment, and monitoring. You build it, you own it.

• Direct partnership with Business, Product, Operations, and other stakeholders.

• You will learn a ton, build on AI, and deliver tangible impact. You will also shape the team's direction, its charter, and its technology choices.

• If you're looking for the best parts of an established company with an AI-first mindset and the agility to move fast, this is your opportunity.

What You’ll Be Doing  
 

1) Key Responsibilities  

• Architect and lead the delivery of scalable, cloud-native software systems across backend and frontend layers.  

• Own end-to-end design and implementation of GenAl and LLM-powered platform capabilities in production and familiarity with Multi Agent orchestration.

• Lead architectural reviews, establish engineering best practices, and set technical direction for the team while championing observability, reliability, and security practices.

• Drive cross-functional technical collaboration with product, data science, security, and infrastructure teams.  

• Mentor junior engineers through pairing, code reviews, and structured knowledge transfer.  
  
   

2) Required Qualifications  

• Bachelor’s degree in computer science or a related technical field.  

• Hands-on experience with at least one programming language: Python, Go, or TypeScript  <