Global Health Economics & Outcomes Research (HEOR) Associate Director (HYBRID)

Vertex is seeking a talented and motivated individual to join its Global Health Economics & Outcomes Research (HEOR) group in Boston, MA. The Health Economics & Outcomes Research Associate Director will participate in the shaping and execution of HEOR strategies that optimize the value  proposition and supporting evidence of Vertex’s innovative renal pipeline asset, povetacicept, a dual inhibitor of the BAFF and APRIL pathways, currently in phase III.

This position reports to the Senior Director Global HEOR, Kidney. 

Key Duties and Responsibilities: 

​• Leads others to execute complex HEOR evidence generation including, cost-effective  analysis and budget impact models, prospective and retrospective observational studies, ITCs, meta-analyses and systematic reviews, patient reported outcomes measure  development and validation, and other research as needed to support the asset value 

• Gathers and synthesizes insights from Payers, KOLs and HEOR experts; stays current with scientific and policy trends and best practices and applies strategic and content expertise to strategy planning.

• Applies best practices to provide key input to the design of Vertex observational research studies 

• Collaborates with the medical communications teams on publication strategy and ensure that dissemination of HEOR evidence is timely and has maximum impact 

• Partners and works closely with Global Pricing and Market Access to support production of GVD and Value Narrative 

Knowledge and Skills: 

• Strong track record of publication in peer-reviewed journals 

• Provides technical expertise in HEOR and can formulate and lead creative research  projects and ensure conduct is technically and scientifically rigorous and reflects best HEOR practices 

• Strong verbal and written communications skills, including presentation skills to communicate difficult concepts and persuade others; comfortable communicating complex concepts and adapting presentation style to a variety of audiences.

• Ability to apply knowledge of US healthcare system, global health technology appraisal requirements, and clinical development, to identify evidence gaps and formulate evidence generation strategies.

• Understanding of the legal and regulatory environment of the pharmaceutical industry, with spotless history of compliance and ethical workplace conduct 

Education and Experience: 

• Advanced degree (PhD, MD, Master's degree, MPH, or PharmD) in a relevant discipline. 

• Typically requires 8 years of experience, with substantial background in HEOR, or the equivalent combination of education and experience