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Senior IT Infrastructure Engineer
SystimmuneUnited Statesfull_timeVerifiedPosted 6 May 2026
💰 $135,000/yr($100,000/yr – $135,000/yr)
About the role
SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.
We are seeking a highly skilled Senior IT Infrastructure Engineer to join our growing organization. While we are not a startup, we are in an active growth phase, and this role requires someone who thrives in a dynamic, evolving environment. This is a hands-on, high-impact position where you will work closely with IT leadership to manage and scale a complex hybrid infrastructure spanning on-premises data centers and cloud environments. You will play a critical role in maintaining stability while also driving improvements, standardization, and growth.
We are looking for a self-driven, solution-oriented engineer who is comfortable wearing multiple hats, taking ownership of large initiatives, and operating at a senior technical level.
This role requires full-time onsite presence in our Redmond, WA office, with a planned relocation to our new Bothell, WA facility in fall 2026.
Key Responsibilities
Qualifications
Work Environment
Primarily on-site with local travel. Supports distributed teams across the U.S. High-autonomy, collaborative environment.
Compensation and Benefits:
The expected base salary range for this position is $100,000 - $135,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s level qualifications, experience, and skills.
SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.
We offer an
We are seeking a highly skilled Senior IT Infrastructure Engineer to join our growing organization. While we are not a startup, we are in an active growth phase, and this role requires someone who thrives in a dynamic, evolving environment. This is a hands-on, high-impact position where you will work closely with IT leadership to manage and scale a complex hybrid infrastructure spanning on-premises data centers and cloud environments. You will play a critical role in maintaining stability while also driving improvements, standardization, and growth.
We are looking for a self-driven, solution-oriented engineer who is comfortable wearing multiple hats, taking ownership of large initiatives, and operating at a senior technical level.
This role requires full-time onsite presence in our Redmond, WA office, with a planned relocation to our new Bothell, WA facility in fall 2026.
Key Responsibilities
- Manage and support a hybrid infrastructure (on-prem + cloud)
- Administer Palo Alto firewalls, Cisco switches and routers, VMware and Hyper-V environments
- Design and troubleshoot network configurations including site-to-site VPNs and routing
- Oversee Microsoft 365 administration including licensing and user management
- Manage remote tools such as Datto RMM, TeamViewer, GoToAssist
- Support conference room systems (Logitech)
- Administer NAS/storage systems for hypervisors
- Work across Windows Server and Linux (Ubuntu, CentOS, Debian)
- Assist with SQL systems (preferred)
- Support Azure/cloud infrastructure (plus)
- Create documentation, SOPs, and diagrams
- Support users across multiple locations
Qualifications
- Bachelor's degree in Information Technology, Information Management Systems, Computer Science, or a related field required.
- Minimum of 5–8 years of hands-on IT infrastructure experience, including server administration, enterprise networking, and end-user support; prior experience in a senior or lead capacity is strongly preferred.
- Life Sciences environment experience
- Waters Empower, UNIFI, Connect
- Geneious Prime, Dotmatics Discovery Studio, Tableau
- Regulated environments (GxP, HIPAA)
- Strong network engineering expertise
- Independent troubleshooting ability
- Comfort in a fast-paced environment
- Proactive, go-getter mindset
- Ability to leverage AI/tools for research
- Strong documentation and communication skills
- Ownership and accountability
Work Environment
Primarily on-site with local travel. Supports distributed teams across the U.S. High-autonomy, collaborative environment.
Compensation and Benefits:
The expected base salary range for this position is $100,000 - $135,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s level qualifications, experience, and skills.
SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.
We offer an
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