Senior Global Clinical Operations Program Director

Job Title: Senior Global Clinical Operations Program Director

Location: Barcelona

Hybrid Working Model: 3 days per week from office

Introduction to role:

Are you ready to steer global cell therapy programs that turn bold science into meaningful outcomes for patients? Do you see yourself converting Target Product Profiles into operational reality at speed and scale while raising the bar for delivery? In this senior leadership role, you will shape and execute the clinical development plan for a high-impact cell therapy portfolio. Partnering closely with the Global Product Team and leading the Clinical Program Team, you will bring strategic clarity, operational excellence, and innovative delivery models to complex, multinational programs. Your leadership will ensure each study in the program delivers to scope, time, cost, quality, and risk parameters—building the evidence that advances regulatory submissions and post-approval value.

Accountabilities:

- Program Leadership: Own end-to-end operational delivery of the agreed clinical development plan for cell therapy programs, translating strategy into actionable program roadmaps and ensuring timely escalation and decision-making with the Global Product Team.

- Clinical Strategy and Design: Provide operational input to clinical strategy, study design, feasibility, and country selection; optimize delivery models and risk management to accelerate start-up and execution without compromising quality.

- Cross-Functional Alignment: Partner with clinical and biometrics leadership to align goals, clarify priorities, and enable high-performing, outcome-focused Clinical Program Team execution.

- CPT Leadership and Ways of Working: Establish team structure, governance rhythms, and clear accountability to drive efficient, effective program management across multiple studies and geographies.

- Line Management: Lead and develop global study and program leaders, setting a high-performance bar and coaching for impact, growth, and collaborative excellence.

- Regulatory Delivery: Accountable for clinical operations components of regulatory submissions, supporting regulatory interactions, inspection readiness, and post-registration product maintenance activities.

- External Partnerships: Serve as the program-level operational interface and decision-maker with CROs, academic partners, alliances, and other vendors; negotiate delivery commitments and manage performance.

- Governance and Compliance: Ensure rigorous adherence to company-wide governance controls, including financial oversight, continuous assurance, and clinical trial disclosure; maintain accurate program planning in business reporting systems.

- Budget and Resource Management: Lead forecasting and control across cost, FTEs, and timelines; build compelling business cases and dynamically manage resources to deliver against program priorities.

- Change Leadership and Innovation: Be an early adopter and ambassador for new ways of working, piloting innovative approaches and embedding improvements that enhance efficiency and outcomes. - Functional Impact: Lead non-drug project work and cross-functional improvement initiatives; contribute as a subject matter expert to shape standards, tools, and capabilities.

- Talent Development and Networking: Mentor and coach colleagues across functions; actively share best practices internally and externally to strengthen delivery and scientific relevance.

Essential Skills/Experience:

- Bachelor of Science/Master of Science degree in a related discipline, or equivalent work experience; advanced degree preferred.

- Extensive global drug development leadership or equivalent leadership experience demonstrated across a variety of roles.

- Extensive experience across the product life cycle, with experience in cell therapy development and ideally across multiple therapeutic areas.

- Clinical operations knowledge with a strong track record of delivery.

- Comprehensive knowledge of the clinical and pharmaceutical drug development process.

- Proven ability to develop programs to meet business goals and to assess business risk versus potential value; ability to understand global business requirements.

- Significant experience of program management and use of project management techniques in complex projects, including resourcing, financial management, and business case development.

- Proven ability to develop successful collaborations with internal stakeholders and ext