Manager, Master Data Management

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!  

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics. 

Why Join our IT team? 

• Innovative Environment: Leverage the latest technologies to drive digital transformation in cancer immunotherapy. From cloud platforms to advanced data solutions, your expertise will help build the backbone that powers groundbreaking science. 

• Collaborative Culture: Work alongside scientists, engineers, and global IT experts in a truly cross-functional setting. You’ll have the opportunity to share ideas, solve complex challenges, and grow your technical and leadership skills in a supportive environment. 

• Global Impact: Your IT solutions will enable researchers and clinicians worldwide to work faster, smarter, and more securely. Every system you optimize and every process you streamline contributes directly to improving patient outcomes across the globe. 

We are seeking a Manager, Master Data Management, to support our IT Validation team. This role will lead Immatics’ master data strategy during the transition to SAP S/4HANA (go-live: January 1, 2026), overseeing data migration and serving as the long-term governance authority. The Manager will ensure data accuracy, compliance, and consistency across R&D, clinical, and supply chain operations. 

FLSA Classification: Salary, Exempt  
Schedule: 8:00 AM – 5:00 PM; Monday to Friday; On-site  
Reports to: Vice President, IT  
Location: 13203 Murphy Road Suite 100 Stafford, TX 77477  

What You’ll Do: 

As a Manager, Master Data Management , you will play a key role in supporting our IT Validation Operations:  

• Lead the S/4 data‑migration and master data work‑stream (strategy, mapping, cleansing, load & reconciliation). 

• Deploy SAP S/4 HANA to centralize material, supplier, customer and finance master data.  

• Establish and chair the enterprise‑wide master data management. 

• Define data standards, policies and stewardship model aligned to GxP, SOX and other regulations. 

• Orchestrate data preparation, cleansing, load, and validation for each release wave/PI, including mock loads, cutover, and post‑go‑live stabilization with clear Go/No‑Go quality gates. 

• Align cross‑functional stakeholders (Clinical, Manufacturing, Quality, Supply Chain, Finance, Commercial) to deliver on‑time, complete data and close gaps quickly.