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Senior Manager, Data Management
Rhythm PharmaceuticalsUnited Statesfull_timeVerifiedPosted 28 Jan 2026
💰 $215,000/yr($135,000/yr – $215,000/yr)
About the role
Company Overview
Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients and their families living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases and provide meaningful support for healthcare providers and patients and their families. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.
Opportunity Overview
The Senior Manager, Data Management acts as the Lead Data Manager for multiple clinical studies and/or a clinical development program. The successful candidate will provide leadership and guidance for all phases of clinical studies from the EDC study design through to study closeout. They will be responsible for the oversight and management of clinical data management activities outsourced to CROs. The Senior Manager, Data Management will also contribute to the Rhythm data management operational improvement efforts to identify, develop, and implement departmental standards, applications, processes, and training.
Responsibilities and Duties
Qualifications and Skills
Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients and their families living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases and provide meaningful support for healthcare providers and patients and their families. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.
Opportunity Overview
The Senior Manager, Data Management acts as the Lead Data Manager for multiple clinical studies and/or a clinical development program. The successful candidate will provide leadership and guidance for all phases of clinical studies from the EDC study design through to study closeout. They will be responsible for the oversight and management of clinical data management activities outsourced to CROs. The Senior Manager, Data Management will also contribute to the Rhythm data management operational improvement efforts to identify, develop, and implement departmental standards, applications, processes, and training.
Responsibilities and Duties
- Responsible for the oversight of Clinical Data Management activities outsourced to CROs to ensure adherence to scope of work and service agreements
- Develop Data Management metrics and key performance indicators to aid in the oversight and management of CRO partners
- Responsible for CRO adherence to project timelines, from study startup through study closeout, ensuring high quality and integrity of all deliverables
- Collaborate with clinical study teams and vendors to ensure project deliverables are met, including data acquisition, quality data review and reporting in compliance with GCP, SOPs and regulatory requirements
- Review data via listings and visualization tools to report on performance and quality; review will be performed with clinical data within studies and across multiple studies for trend analysis
- Contribute to the development, review and implementation of Clinical Data Management processes, policies and SOPs
- Participate in vendor qualifications and audits
- Oversee the planning, execution, and maintenance of major projects and initiatives, if required.
- Lead data management study inspection readiness activities and the support of submission activities as needed.
- Train and mentor DM staff or members of the clinical trial team on processes, projects, systems, and programs.
- Perform hands-on data management responsibilities, if required.
Qualifications and Skills
- Bachelor’s degree in a science-related discipline, or equivalent work experience
- 6+ years working in clinical data management at a Sponsor organization with experience across multiple indications and EDC platforms
- Experience developing initiatives designed to promote efficiency and productivity for data management operations
- Extensive knowledge of clinical data management outsourcing models including functional-service providers and full-service CROs
- Experience leading a team of CRO data managers to ensure the timely provision of DM deliverables
- Advanced hands-on knowledge of data management processes and EDC systems
- Knowledge of regulatory requirements (e.g. ICH, GCP, HIPAA)
- Experience with data visualization, analytics and reporting tools such as elluminate or SpotFire
- Strong project management skills, and ability to effectively lead and collaborate with various business functions
- Demonstrated ability of working on multiple projects simultaneously, independently managing competing priorities, and define tracking tools to manage projects
- Experience in solving extremely complex and increasingly difficult problems, independently taking the appropriate corrective action, and identify and implement improvements. Able to review, interpret and evaluate clinical data
- Demonstrate initiative, sound judgment and flexibility; possess effective time management and organizational skills; and be able to work under deadlines and on multiple projects simultaneously
- Excellent written and verbal communication sk
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