Senior R Developer (m/f/d)

<p>We are seeking a talented and motivated <strong>Senior R Developer (f/m/d)</strong> to help us develop our R-based toolchain for a cutting-edge modeling and simulation software platform within an interdisciplinary environment as part of the core development team of the cross-industry, open-source project “Open Systems Pharmacology” Suite (OSP Suite with PK-Sim®, MoBi®, and R Packages, <a href="http://www.open-systems-pharmacology.org/">www.open-systems-pharmacology.org</a>).</p><p>ESQlabs is an innovative, internationally acting Contract Research Organization and a global leader in the development and application of the OSP Suite (www.open-systems-pharmacology.org). We are a research-focused provider of specialized computational analyses in the life sciences industry.<strong><br/></strong></p><p><strong><br/></strong></p><p><strong>Role</strong></p><p>As a part of the ESQlabs software development team, you will develop the <strong>R package environment of the OSP Suite</strong> in collaboration with highly experienced software developers</p><ul> <li>Development of R workflows supporting Model Informed Drug Development (MIDD) and toxicological risk assessment</li> <li>Development of R packages for modeling and simulation workflows with mathematical models created with the OSP software (integration of R and .NET)</li> <li>Development of R packages for parameter estimation for mathematical models (leveraging machine learning, non-linear mixed effects, log-likelihood, Bayesian modeling)</li> <li>Solutions for data visualization (ggplot, etc.) and reporting (RMarkdown/Quarto)</li> <li>Shiny applications</li> <li>Compilation of training material for internal and external users</li> </ul><ul> </ul><p>In this role, you can help redefine the standards for analysis workflows used for M&amp;S and data analysis in the Life Sciences. With your contribution, we aim to make this software the market leader and a go-to tool for the industry.</p><p>You can find a selection of R packages developed by or with ESQlabs:</p><ul> <li>esqlabsR - <a href="https://github.com/esqLABS/esqlabsR">https://github.com/esqLABS/esqlabsR</a></li> <li>ESQapp - <a href="https://github.com/esqLABS/ESQapp">https://github.com/esqLABS/ESQapp</a> </li> <li>OSPSuite-R - <a href="https://github.com/Open-Systems-Pharmacology/OSPSuite-R">https://github.com/Open-Systems-Pharmacology/OSPSuite-R</a></li> <li>OSPSuite.ParameterIdentification - <a href="https://github.com/Open-Systems-Pharmacology/OSPSuite.ParameterIdentification">https://github.com/Open-Systems-Pharmacology/OSPSuite.ParameterIdentification</a></li> </ul><p><strong><br/></strong></p><p><strong>Required skills &amp; experience</strong></p><ul> <li>Master’s degree in quantitative sciences such as data science, engineering, applied mathematics, or a similar field</li> </ul><ul> <li>A track record of developing and maintaining robust R packages used in production or research environments</li> <li>Good understanding of advanced R programming practices (e.g., metaprogramming, S3/R6 OOP concepts)</li> <li>Proficiency with Git and collaborative development workflows (e.g., pull requests, branching, tagging)</li> <li>Experience configuring CI/CD pipelines for R packages using tools like GitHub Actions, AppVeyor, or similar</li> </ul><ul> <li>Passion for and understanding of Life Sciences, ideally with experience working in pharmacometrics or a related field.</li> <li>Strong background in statistical modeling and data analysis, preferably in clinical, biomedical, or regulatory environments</li> <li>Agile mindset, problem-solving skills, and willingness to embrace change and new technologies</li> <li>Strong organization skills and ability to handle multiple tasks simultaneously</li> <li>Ability to prioritize tasks effectively and deliver high-quality work under tight timelines</li> <li>Great critical-thinking and problem-solving skills</li> <li>Fluency in English (oral and written)</li> </ul><p><br/></p><p><strong>Further qualities that will put you in the spotlight</strong></p><ul> <li>Experience working in pharmacokinetics/pharmacodynamics</li> <li>Experience with R packages validation for the pharmaceutical industry (GxP)</li> <li>Experience with agile practices (SCRUM, CI/CD, PP)</li> <li>Experience in domain-specific software development</li> <li>Experience with C++ or .NET</li> <li>Experience in Cloud-Technologies such as Microsoft Azure, AWS, …</li> </ul><p><br/></p><p><strong>What's in store for you</strong></p><p>The dynamic team behind esqLABS unites people with different backgrounds, spanning disciplines like pharmaceutical sciences, physics, bioinformatics, mathematics, data science, and software engineering. Our trust in each other, our open-mindedness, and our constant quest for excellence and innovation unite us. We value flat hierarchies, whe