Senior Director, Clinical Operations

<div class="content-intro"><p>At Pliant, we believe differentiated science can make a meaningful impact. We see our success as a direct result of the central role that each team member plays in advancing our mission to develop therapies that target the disease at its source. We are seeking creative, curious and collaborative individuals who&nbsp;<strong>dare to succeed</strong>, are committed to&nbsp;<strong>making an important impact</strong>&nbsp;on patient’s lives and will help us build&nbsp;<strong>one Pliant</strong>!</p></div><h1><strong>Description</strong></h1> <p>Reporting to the SVP of Development Operations, the Senior Director, Clinical Operations is responsible for the implementation and management of functional processes, tools and resources to enable delivery of Pliant's clinical programs with excellence. The Sr. Director will collaborate closely with a cross-functional team in a fast-paced, high-growth environment to ensure all clinical trials in the portfolio are executed on time, within budget, and in accordance with applicable GCP/ICH guidelines, other regulatory requirements and the corporate goals and objectives. The Sr. Director will also provide leadership to the Clinical Operations function, serving as a functional lead in cross-functional environments, and accountable for organizational initiatives.&nbsp;</p> <p>This is a hybrid role based in South San Francisco (3 days onsite per week).</p> <h1><strong>Responsibilities</strong></h1> <ul> <li>Accountable for the comprehensive oversight and management of all clinical studies in the portfolio, including providing strategic and tactical&nbsp;guidance to study teams to ensure timely operational execution and&nbsp;completion of clinical trials.</li> <li>Accountable for ensuring and maintaining ICH/GCP compliance and inspection-readiness across clinical programs.</li> <li>Develop and manage the resourcing plan for Clinical Operations including the assignment and allocations to clinical studies and leading the hiring of new team members, as needed.</li> <li>Accountable for developing detailed clinical program budgets and managing spend in accordance with plans.</li> <li>Coach and manage multiple direct reports; and mentor junior members of the team.</li> <li>Provide oversight of clinical research organizations (CROs) and other key vendors to ensure efficient, effective, and high-quality deliverables.</li> <li>Serve as the primary escalation point for issues related to operational execution and risk mitigation.</li> <li>Oversee the development of vendor specifications, project scope, and accountable for vendor selection.</li> <li>Oversee the establishment of KPIs, KRIs and stage-appropriate governance s