Senior Medical Advisor

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

About 

Madrigal Pharmaceuticals is a science-driven company committed to transforming treatment for patients with metabolic-dysfunction associated steatohepatitis (MASH). As a leader in this field, they emphasize integrity, collaboration, and innovation while striving to improve patient outcomes. Their groundbreaking therapy is set to revolutionize MASH treatment, and they are building a high-performing commercial team to drive its adoption. Madrigal offers a dynamic and supportive environment were collaboration and innovation drive success. The team is passionate about delivering transformative therapies to patients in need. If you thrive in a results driven, patient-centric culture, we invite you to be part of this journey. Our mission is to transform the standard of care for patients suffering from NASH by delivering groundbreaking therapies that improve liver health and prevent disease progression.

Position Summary 

The Medical Advisor will plan and lead pre/launch activities in the therapeutic field of metabolic dysfunction associated steatotic liver disease (MASLD/MASH). The Medical Advisor is the medical specialist within their field and an expert in the medical affairs landscape within their territory. An understanding of the healthcare system within your country/region and a good understanding of diagnostic pathways for patients in this field is important, as well as gathering relevant insights. This is a highly valuable member of the medical team who represents externally by engaging in scientific discussions with targeted thought leaders, clinical trial investigators, and other healthcare professionals. 

Key responsibilities 

• Demonstrate support for clinical trials and engage with external experts on the generation of scientific data 

• Collaborate with clinical organizations to enhance patient enrolment in company sponsored clinical trials by identifying appropriate trial sites and interacting with investigators in ongoing trials 

• Deeply understand the fatty liver therapeutic area (MASLD/MASH), key stakeholders, and healthcare landscape (i.e. reimbursement/access, diagnostic, testing) in your territory 

• Help execute country medical plans locally by providing medical expertise in MASLD/MASH and engaging with the medical community in Hepatology, Gastroenterology, and Endocrinology 

• Attend relevant scientific meetings and conferences and support development of summaries of key data, presentations or symposiums 

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