Principal Scientist, Molecular & Complex Cell Technologies

Why Patients Need You 

This position will provide the opportunity to make a positive impact during early stages of cancer drug development by optimizing the process of evaluating drug candidates and de-risking potential toxicities.  These efforts will ultimately contribute to the larger goal of making therapeutics safer and more effective for cancer patients.

What You Will Achieve

The successful candidate will work with multidisciplinary project teams to advise, develop and implement cutting-edge in vitro technologies such as complex cell culture, organoids, and microphysiological systems to support therapeutic platform development, target evaluation, candidate optimization and selection, and mechanistic investigations. 

How You Will Achieve It

The candidate will have the ability to work independently with the support of laboratory personnel. The position is highly collaborative across local and global functions within Research and Development and external partners.

• Collaborate with multidisciplinary project teams to develop and implement in vitro Novel Alternative Methods (NAMS) for screening, candidate selection, and/or mechanistic studies to de-risk toxicity.
• Serve as a local subject matter expert and point person for collaborations with the Cellular & Molecular Investigative Toxicology Team in Groton CT
•  Liaise with Research team members and Toxicology program leads to develop, implement, and interpret in-vitro tissue-based assays to generate data that may inform go/no go decisions.
• Network within Drug Safety R&D (DSRD) and other group global experts to share learnings and enhance understanding of the strengths and limitations of NAMs.
• Manage and coordinate work involving NAMs with external partners.
• Supervise a small technical group to run, collect data, and perform analyses.
• Keep up to date with emerging literature and science in the NAMs, Microphysiologic Systems, and Toxicological Sciences  
• Stimulate interest in the respective area through publication, presentation, and networking internally and externally.

Qualifications

Must-Have

• Ph.D. degree in cell/molecular biology, toxicology, immunology, or related field with 3+ years post-doc experience. Expertise in tissue/cell culture and in vitro analytical methodologies  .
• Strong organizational, interpersonal, teamwork, written and verbal communication skills.
• Ability to prioritize and manage multiple projects and activities while managing timelines.

Nice-to-Have

• 3 year’s experience in biotech/pharm
• Experience working with microphysiological systems and familiarity with complex cell cultures
• Passionate about developing and working with novel alternative methods
• Knowledge of toxicological studies

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Occasional travel may be requested. Laboratory work requires adherence to safe work practices and procedures such as use of Personal Protective Equipment (gowning, gloves, protective eyewear, etc.).

Other Job Details:

• Location: Bothell, WA (Seattle Area)
• Eligible for Relocation Package – YES
• Work Location: On Premise.

PHYSICAL/MENTAL REQUIREMENTS

Position requires activities such as walking, standing, sitting on a stool, and light lifting as would be incurred in a laboratory environment. Laboratory work requires adherence to safe work practices and procedures such as use of Personal Protective Equipment (gowning, gloves, protective eyewear, etc.).

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Occasional travel may be required.

 

The annual base salary for this position ranges from $109,400.00 to $182,300.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or