Sr. Scientist

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.
 

Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact.
 

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.

Job Description
 

Biologics Analytical Operations

Gilead Sciences, Inc. is a research-based biopharmaceutical company founded in 1987. Together we deliver life-saving therapies to patients in need. With the commitment and drive you bring to the workplace every day, you will be part of a team that is changing the world and helping millions of people live healthier, more fulfilling lives. Our worldwide staff is a close community where you can see the tangible results of your contributions, where every individual matters, and everyone has a chance to enhance their skills through ongoing development. Our scientific focus has resulted in marketed products that are benefiting hundreds of thousands of people, a pipeline of strong late-stage drug candidates, and unmatched patient access programs to ensure medications are available to those who could otherwise not afford them. By joining Gilead, you will further our mission to address unmet medical needs and improve life by advancing the care of patients with life-threatening diseases.

The successful candidate will possess a detailed understanding of proteins and carbohydrates. The candidate must be highly motivated to contribute to the research and development of biologics targeting unmet medical needs through biochemical characterization and novel method development supporting clinical and commercial programs. Experience in several of the following fields is strongly desired: analytical chemistry, biochemistry, biological mass spectrometry, high performance or ultra-performance liquid chromatography, electrophoretic separations, enzymology, statistics, chemical and biophysical structural elucidation, and bioinformatics.

*At a future date, this position will relocate to the corporate HQ in Foster City, CA.

Essential Duties and Job Functions:

• Works as part of a team to support late-stage assay development by performing mass spectrometry to characterize molecules, degradation pathways, and define critical quality attributes in a phase-appropriate context.

• Contributes to analytical method development and qualification to support protein characterization activities.

• Develops new assays to gain competitive advantages over standard industry practices.

• Supports comparability and stability studies by mass spectrometry.

• Operates, maintains, and troubleshoots Waters, Sciex and Bruker QTOFs and Thermo Orbitrap mass spectrometers.

• Works on complex problems where analysis of situations or data requires evaluation of intangible variables requiring regular use of intelligence, logic, ingenuity, and creativity.

• Works in collaboration with junior and senior team members to advance the development of state-of-the-art techniques to characterize substances, assays, and tools.

• Represents the Structure Characterization group in cross-functional project teams.

• Participates in technology transfer of assays from analytical development to QC and external CRO/CMOs.

• Participates in process comparability studies and coordinates analysis of in-process and product-related impurities as needed.

• Responsible for conducting scientific research for the development of drug candidates or research support of marketed drugs.

• Advises project teams on the planning and execution of laboratory experiments, considering economic, regulatory and safety factors.