Senior Scientist Translational Research - Molecular Based Assays

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The successful candidate for the Sr. Scientist position will be a highly motivated and collaborative scientist responsible for developing, validating and implementing molecular based assays to support exploratory translational research in the clinical setting within the Translational Research department in the Cancer-Oncology and Cellular Therapy Thematic Research Center.

The candidate will collaborate closely with the Biomarker Lead to establish assays in alignment with the program's translational strategy.  The individual will provide end to end support of the clinical assays lifecycle which may include liaising with external labs, establishing data specifications, checking quality of data generated, and supporting interpretation of the results.

Position Responsibilities

In the role as a Senior Scientist within the Translational Research team, the ideal candidate:

• Applies scientific and / or technical skills and functional knowledge to conduct experiments / research / studies in assigned area

• Adapts standard methods and techniques by applying breadth of knowledge and prior work experience

• Makes decisions that impact entire work group / project team

• Contributes to initiatives related to continuous improvement or development of new approaches / technologies

• Starts to develop and implement approaches to new technology and take calculated risks

• Leads discussions and makes presentations in multidisciplinary meetings, logically presenting information to convey clear, key messages

• Is expected to explain, persuade, and build alignment for situations

• May represent department or function on program / project team or sub-team

• Serve as a subject matter expert in molecular-based assays, collaborate with project teams and biomarker leads on the fit for purpose design and implementation plan of assays to address key translational questions in early phase clinical trials

• Provide technical guidance on assay selection, design, optimization, qualification and/or validation, and implementation 

• Lead the development and analytical validation of molecular based assays internally and or at external vendors to support our CICT TRC clinical trials globally

• Troubleshoot assay data and technical issues effectively and efficiently with internal teams and external partners

• Apply molecular biology, and biochemical laboratory techniques with efficiency, accuracy, and attention to detail; conduct data analysis, report and represent results independently in collaborative environment to the team and relevant stakeholders

• Lead and collaborate with internal cross-functional teams and external partners to oversee assays at contract research organizations

• Review and author technical documents including protocols, validation reports, publications, regulatory documents, etc.

Basic Qualifications:

• Bachelor’s Degree

  • 7+ years of academic and / or industry experience

Or

• Master’s Degree

  • 5+ years of academic and / or industry experience

Or

• Ph.D. or equivalent advanced degree in the Life Sciences

  • 2+ of academic and / or industry experience

Preferred Qualifications:

• Requires thorough knowledge of varied aspects or a single specialized aspect of own discipline and developed knowledge of other related disciplines

• Is proficient in scientific / technical writing (e.g., regulatory documents, protocols)<