VP, Program Team Leader

Company Overview:

Dyne Therapeutics is discovering and advancing innovative life-transforming therapeutics for people living with genetically driven neuromuscular diseases. Leveraging the modularity of its FORCE™ platform, Dyne is developing targeted therapeutics that deliver to muscle and the central nervous system (CNS). Dyne has a broad pipeline for neuromuscular diseases, including clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD) and preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. For more information, please visit https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook. 

Role Summary:

The Program Team Leader (PTL) is a passionate drug developer with a global perspective, who brings adaptable leadership, strategic product development acumen, and relentless pursuit of long-term success for patients and Dyne’s medicines.  The PTL is a highly visible leadership role. Working with an experienced Program Manager and a cross-functional team, the PTL shapes the Program strategy, goals, priorities, and plans, bringing both a ‘future-orientation’ toward the ultimate goal of broad, global commercial access for patients in need, and a “pragmatic-orientation” to chart the path, mitigate risks, cultivate options, and lead through complex drug development decisions.

This role is based in Waltham, MA without the possibility of being a remote role. 

Primary Responsibilities Include:

• Lead a high-performing cross-functional Program Team, focusing on both the “what”, such as strategy, priorities, output, and resources, and also the “how”, such as maintaining a fulfilling, collaborative, and sustainable team environment
• Establish a robust and well-understood Program strategy for bringing a life-changing medicine to patients in need
• Ensure that research, non-clinical, clinical, regulatory, CMC, and commercial strategies and plans are aligned with the overall Program strategy
• Structure and facilitate critical cross-functional decisions within Program Team and senior leadership team, bringing all relevant perspectives to bear while driving to efficient decisions in a fast-paced environment
• Own Program recommendations across stages of the Program to achieve milestones and timelines
• Drive preparation and presentation of materials for Board of Directors and Scientific Advisory Board
• Maintain clear, open, and proactive communication with the senior leadership team and other stakeholders regarding Program strategy, status, priorities, risks and needs, and facilitate appropriate decision-making
• Keep abreast of emerging developments regarding research and development in the fields of muscle diseases and oligonucleotide drug discovery and development
• Build visible, constructive, and credible presence within KOL and patient community for relevant disease areas
• Participate in business development activities, as needed, including opportunity evaluations and due diligence
• Provide a motivating leadership example within Dyne more broadly during periods of rapid growth
• Responsibly steward the Program budget in collaboration with finance and functional leaders
• Foster a culture of collaboration, innovation, discovery, and cutting-edge research focused on scientific excellence, open communication, and continual improvement
• Actively coach team members to achieve their best and support to mitigate gaps in skill or capacity
• Consider needs of the Program in context of Dyne corporate strategy and priorities, as primary advocate for the Program among Dyne senior leadership
• Lead with Dyne’s core values at the forefront

Education and Skills Requirements

•  Experience in Phase 1-3 drug development is required; product launch/early commercialization experience a strong plus
• Proven and respected leader with:
  • Advanced degree in Medical or Life Science, MD, PhD or MBA or equivalent
  • 12+ years of experience in pharmaceutical industry in leadership positions in drug development and proven track record in driving Programs through IND, early clinical, pivotal stages and approval
  • And/or at least 12 years in pharmaceutical industry in significant development and/or commercial leadership or general management positions including working with development teams in cross-functional setting, with exceptional track record of delivering on business objectives, activity/milestones leading to filing and launching, and strong knowledge of neuromuscular diseases
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