Senior Software Engineer, Bioinformatics

Company Description

Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary blood tests, vast data sets and advanced analytics. The Guardant Health Oncology Platform leverages capabilities to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs across all stages of the cancer care continuum. Guardant Health has launched liquid biopsy-based Guardant360®, Guardant360 CDx and GuardantOMNI® tests for advanced stage cancer patients. These tests fuel development of its LUNAR program, which aims to address the needs of early stage cancer patients with neoadjuvant and adjuvant treatment selection, cancer survivors with surveillance, asymptomatic individuals eligible for cancer screening and individuals at a higher risk for developing cancer with early detection. 

Job Description

This individual will contribute to development of software and bioinformatics analysis pipelines used to process patient samples and analyze their genomic profiles based on a simple blood draw. This position is part of a high impact team responsible for developing core data analysis and software capabilities for the industry leading cancer diagnositic products offered by Guardant health. This position is responsible for design, implementation, optimization and testing of software components and data analysis pipelines. This position colaborates with Guardant Health’s research and development teams and contributes to development of products that enhance Guardant Health’s leadership position in cancer testing.

Essential Duties and Responsibilities:

• Develop software using C++ and Python in Unix based enivorment with focus on high performance, robustness and extensibility.
• Contribute to proto-typing, development, optimization and validation of bioinformatics analysis algorithms using C++, R and Python
• Provide written documentation and specifications of software products and services.  Preferably in a regulated environment such as IVD or CLIA.
• Contribute to all aspects of software development in an agile environment including documentation, design, development, and testing of features and sub-systems.
• Work collaboratively with scientists to comprehend project objectives, analyze problems, and evaluate and provide informatics solutions.
• Innovate and contribute to development of novel technologies to help advance genomics research and precision medicine.

Qualifications

• M.S. in Computer Science or related field or equivalent experience
• 4+ years experience developing software in unix based environments using C++ and Python
• Demonstrated expert knowledge using object-oriented programming and design patterns in production environments
• Working knowledge of tools like Jenkins, Docker (or other virtualization technologies)
• Experience with developing software or data analysis algorithms in the field of Bioinformatics with familiarity to standard bioinformatics tools and file formats is strongly preferred
• Understanding of concepts like Next Generation Sequencing, Oncology, Liquid biopsies etc., is highly advantageous
• The following experience is not required but is highly desired: working with compute clusters (SGE, HPC, Mesos, etc), AWS
• Effective communicator with written and verbal fluency in English
• Self-motivated individual with ability to work well as part of a team in a rapid-pace startup environment

Additional Information

Hybrid Work Model: At Guardant Health, we have defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.

Covid Vaccination Policy:  Starting January 7, 2022, Guardant Health will require all employees to be fully vaccinated to either (a) establish that they have been fully vaccinated against COVID-19; or (b) request and obtain an approved exemption from Guardant’s COVID-19 U.S. Vaccination Policy as a reasonable accommodation, as consistent with applicable laws.  An employee is considered fully vaccinated against COVID-19 two weeks after receiving the second dose of a two-dose vaccine or one dose of a single-dose vaccination. Acceptable vaccines are approved or under emergency use authorization by the U.S. Food and Drug Administration (FDA) and/or the