Scientist l, Immunology

Why Sarepta? Why Now?
The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold leadership positions in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs), and we currently have more than 40 programs in various stages of development in gene therapy, RNA and gene editing. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.
 

We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.
 

What Sarepta Offers

At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas:

• Physical and Emotional Wellness

• ​Financial Wellness

• Support for Caregivers
   

For a full list of our comprehensive benefits, see our website: https://www.sarepta.com/join-us
 

The Importance of the Role

This is an exciting opportunity for a highly motivated and creative individual to work in a key drug discovery group in our research organization, and play a central role in applying and managing immunology and assay development studies. The successful candidate will work in the lab conducting immuno-assays to support the advancement of Gene Therapy. The candidate will closely with cross-functional teams, such as research scientific leads, research and lab operations, and program management. The individual will be responsible for creation of project plans, identifying and tracking critical path/activities, risks, contingencies, and alternatives and communicating routinely with cross-functional teams. The individual will oversee project teams in support of in-process and final project characterization, they will act as an immunogenicity SME for methods conducted internally and externally at contract research organizations. The successful candidate will manage the immunology department to support immunology research and capabilities for technological advancements.

The Opportunity to Make a Difference

• Serve as subject matter expert on gene therapy pre-clinical development for existing and new programs.
• Conduct immunology assays and laboratory activities to support clinical trials and R&D studies.
• Conduct laboratory activities in Sarepta in-house laboratory, interacts with research, translational biology and bioanalytical groups.
• Ownership of a new or ongoing immunology assay to help drive pre-clinical development through stage gates and key milestones to support regulatory and clinical development.
• Serve as study director for clinical and non-clinical testing studies
• Author scientific method validation plan, testing study and validation reports
• Maintains compliant laboratory records, consistently and accurately documents all laboratory activities in laboratory notebooks and internal technical reports.
• Work in cross-functional manner to design and plan pre-clinical GT studies in collaboration with other research group and other key stakeholders.
• Author development reports and powerpoint slide decks, study protocols, and pre-clinical study reports to communicate ongoing activities internally and externally.
• Perform other related duties incidental to the work described.

More about You

• Ph.D. with 0-3 years experience in biology or related, immunology preferred
• Hands-on experience with immunological techniques including ELISA, ELISpot assay, MSD, and Flow cytometry.
• Prior experience with human samples (PBMC) is a plus.
• Ability to plan and carry out experiments independently with strict adherence to laboratory methods and SOPs.
• Demonstrates proficient written and oral communication and presentation skills and a documented ability to troubleshoot technical issues.
• Experience with statistical and computer productivity software (i.e. Word, Excel, Outlook, etc.).
• Desire to work in a high-functioning, collaborative team
• Desire to work in a dynamic, fast-paced team environment and to make a difference in the lives of people through our innovative medicines
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