Research Technologist – Cell Therapy Manufacturing (GMP)

Title:

Research Technologist – Cell Therapy Manufacturing (GMP)

Job Type:

Regular

Company:

Health Research, Inc. (HRI) Roswell Park Division

Department:

Center for Immunotherapy

Time Type:

Full time

Weekly Hours:

40

FTE:

1

Shift:

First Shift (United States of America)

Summary:

Join a mission-driven team at the forefront of cutting-edge cell and gene therapies. At Roswell Park’s state-of-the-art GMP Engineering & Cell Manufacturing (GEM) Facility, we are pioneering advanced immunotherapies like CAR-T with the goal of transforming patient care.

We are seeking a Research Technologist to play a key role in the clinical manufacturing of cell therapy products. This is a hands-on, lab-based position within a dynamic cGMP environment, ideally suited for individuals passionate about cellular therapeutics and high-impact translational research. The pay range for the Research Technologist position is $50,456 - $63,986 annually which includes a comprehensive benefits package. The listed pay range reflects the range of potential compensation for this role. The actual offer may vary based on qualifications, skills, and experience

Key Responsibilities:

• Execute end-to-end cell manufacturing processes under cGMP conditions to produce clinical-grade CAR-T and other advanced therapy products.
• Collaborate cross-functionally with Manufacturing Sciences, Process Development, and Quality Assurance teams to ensure seamless technology transfer, facility fit assessments, and process risk evaluations.
• Contribute to continuous improvement initiatives to optimize processes and ensure readiness for clinical trial demands and regulatory audits.
• Maintain accurate, real-time documentation to uphold data integrity and traceability in line with cGMP and institutional requirements.

What You’ll Bring:

• A strong foundation in cell culture and aseptic technique, ideally in a cGMP or regulated environment.
• A detail-oriented mindset with a commitment to quality and operational excellence.
• Effective communication and teamwork skills to support cross-departmental projects.
• Adaptability and drive to work in a fast-paced, evolving field at the intersection of science and medicine.

Why Roswell Park?

• Be part of a nationally recognized cancer center with a legacy of innovation and patient-centered care.
• Access to world-class facilities, resources, and training to support your professional growth.
• The opportunity to directly contribute to life-saving therapies that make a difference in patients’ lives.

Qualifications:

Required Education and Experience

1. Master’s degree in a clinical or scientific discipline; or
2. Bachelor’s degree in a clinical or scientific discipline and the equivalent of one (1) year of full-time experience in a laboratory setting.

NOTE:
Required degrees must have been granted by an accredited school, college or university or one recognized by Roswell Park Comprehensive Cancer Center as following acceptable educational practices.

Preferred Qualifications:

The preferred candidate will have:

• Extensive hands-on expertise in T-cell engineering—including molecular biology techniques and execution of complex analytical assays—to support advanced cell therapy development.
• Demonstrated proficiency in cellular assays, such as flow cytometry, cytotoxicity, and viability testing, with a strong analytical mindset and troubleshooting capabilities.
• Working knowledge of cGMP standards, including experience with production documentation, batch records, and compliance-driven environments.
• Solid foundation in aseptic technique and mammalian cell culture, with a track record of maintaining sterility and culture integrity in high-throughput or regulated settings.
• Strong communication skills, with the ability to convey scientific concepts clearly across cross-functional teams; collaborative, articulate, and committed to scientific excellence.
• Hands-on experience in cell therapy—such as CAR-T, stem cell-based platforms, or other adaptive cell transfer modalities—spanning research, process development, or manufacturing.
• Familiarity with key tools and systems used in clinical and commercial cell therapy production, including CliniMACS Plus/Prodigy, Cocoon, or comparable platforms.
• Exceptional attention to detail, especially in documentation, cleanliness, and organization—critical qualities for maintaining reproducibility and regulatory compliance.

Equal Employment Opportunity Statement

Roswell Park Cancer Institute