Principal Scientist, Lab Platform Disruptive Technologies

We are on a quest for cures and are committed to be the world’s premier, most research-intensive biopharmaceutical company. Our teams combine leading drug discovery capabilities and world-class R&D with the purpose of turning breakthrough science into life-changing medicines. 

Discovery Biologics Disruptive Technologies is seeking a talented and experienced scientist to lead the development and deployment of next-gen lab-based experimental technologies to enable rapid, data-driven biologics discovery. This individual will identify and translate emerging, literature-supported technologies into scalable internal capabilities, with a focus on multiplying both the scale and speed of quantitative data generation (e.g., binding measurements) to advance therapeutic programs via GenAI/ML-driven discovery and iterative design-make-test cycles. The role includes leading a team with expectation for strong hands-on contribution to method development, and will be accountable for driving measurable program and broader organizational impact. The role is based out of our Cambridge, MA facility.   

Key Responsibilities 

• Develop and mature rapid, quantitative and high-throughput lab-based capabilities for biologics hit identification and optimization 

• Build and execute a technology platform roadmap for arrayed and pooled technologies, from proof-of-concept through widespread program adoption 

• Partner effectively with computational protein engineering and data science groups toward efficient, integrated next-gen discovery workflows 

• Drive capability improvements in data richness, speed, throughput  

• Lead a talented team of lab-based scientists 

• As a hands-on individual contributor, realize and maximize program impact of emerging technologies 

• Collaborate effectively across geography and reporting lines  

• Establish rigorous benchmarks (e.g. throughput, speed, reproducibility, data quality) and success criteria 

Qualifications & Experience 

• PhD in Biochemistry, Bioengineering, Chemical Biology, or related field with 7+ years directly relevant industry experience; MS or BS with 12+ years industry experience. 

• Experience developing large-scale, high throughput