Payroll, Benefits & Leave Operations Specialist

Careers with real impact.

Every role at Orsini moves a patient closer to life-changing therapy. We partner with biopharma innovators, healthcare providers, and payers to make access simple, compassionate, and reliable - so no patient is left behind. Make your next role matter.

ABOUT ORSINI

Providing compassionate care since 1987, Orsini is a leader in rare disease and gene therapy pharmacy solutions, built to simplify how patients connect to advanced medicines. Through our comprehensive commercialization solutions including a nationwide specialty pharmacy, patient services hub, home infusion and nursing network, and third-party logistics provider, we work with biopharma, providers, and payors to ensure No Patient is Left Behind™

OUR MISSION

Orsini is on a mission to be the essential partner for biopharma innovators, healthcare providers, and payers to support patients and their families in accessing revolutionary treatments for rare diseases. Through our integrated portfolio of services, we seek to pioneer comprehensive solutions that simplify how patients connect to advanced therapies while providing holistic, compassionate care so that No Patient is Left Behind™.  

CORE VALUES

At the heart of our company culture, the Orsini LIVE IT Core Values serve as guiding principles that shape how we interact with each other and those we serve. These values are the driving force behind our commitment to excellence, collaboration, and genuine care in every aspect of our work.  

COMPENSATION & LOCATION

The compensation starts at $70,000.

This a hybrid position based out of our Elk Grove Village, Illinois location requires 2-3 days in office. Travel to other locations may occur, although minimal.

POSITION SUMMARY

The Payroll, Benefits & Leave Operations Specialist owns the execution, accuracy, and day‑to‑day operational management of payroll, benefits, and leave of absence administration, ensuring employees are paid accurately and on time while maintaining strong financial controls and compliance. 

This role operates as a shared services function supporting both People Operations and Finance, with a primary focus on transactional excellence, vendor coordination, data integrity, and risk reduction. Operating in a multi‑state, regulated environment, this role partners closely with Finance, HR leadership, ADP, benefits brokers, and third‑party administrators to manage payroll, benefits, and leave processes end‑to‑end. 

In addition, this role serves as a primary operational point of contact for employee pay, benefits, and leave inquiries and provides designated onsite operational coverage during scheduled absences, ensuring continuity without disrupting HR leadership or program ownership. 

This role is intentionally execution‑focused and designed to scale as payroll and benefits operations mature, with the potential to transition to Finance ownership in the future. Policy decisions, employee relations, and program design remain with HR leadership. 

ESSENTIAL JOB DUTIES

Payroll Operations & Financial Controls (35–40%) 

• Own end‑to‑end payroll processing for all employee populations, including regular, off‑cycle, retroactive, and final payrolls 
• Ensure payroll is processed accurately, timely, and in compliance with federal, state, and local regulations 
• Own payroll tax registrations, filings, remittances, and agency correspondence in partnership with ADP 
• Manage wage garnishments, deductions, and payroll adjustments 
• Perform payroll reconciliations, variance analysis, and audits to ensure data integrity and financial accuracy 
• Serve as the primary operational contact with ADP for payroll configuration, issue resolution, and system updates 
• ​​​​​​​Support internal and external payroll audits and provide documentation and reporting as required 

Benefits Administration & Vendor Management (20–25%) 

• Own day‑to‑day administration of employee benefits programs, including eligibility, enrollments, life events, and terminations 
• Execute operational aspects of open enrollment, including timelines, system setup, vendor coordination, and post‑enrollment audits 
• Maintain accurate benefits deductions and perform regular carrier and billing reconciliations 
• Serve as the primary operational contact with benefits brokers, carriers, COBRA administrators, and related vendors 
• Coordinate benefits data feeds and resolve discrepancies between HRIS, payroll, and vendor systems 
• ​​​​​​​Respond to employee inquiries related to benefits coverage, deductions, and enrollment logistics