Manager, Data Management Science

Manager, Data Management Science

Job Title:

Manager, Data Management Science

Department / Cost Center:

Data Management Science / cc256

Reports to (Job Title):

Director, Data Management Science

Job Code:

Location:

Preferable San Rafael or Brisbane

(Remote / Flexible allowed dependent on candidate)

Date Prepared:

OCT-2025

Full-Time     Part-Time

Regular     Temporary

Exempt     Non-Exempt

OVERVIEW: Data Science, Data Management Science (DMS)

BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating, and have few, if any, treatment options. BioMarin aims to improve life and health outcomes for people with rare diseases by advocating the use of innovative BioMarin therapeutics, advancing the standard of care, and providing personalized support and services globally. 

BioMarin Global Data Science (GDS) is responsible for designing, capturing, analyzing, and presenting data that can drive key decisions for Clinical Development, Medical Affairs, and other business areas of BioMarin. With a quality-by-design culture, GDS builds quality data that is fit-for-purpose to support statistically sound investigation of critical scientific questions. The GDS team develops solid analytics that are visually relevant and impactful in supporting key data-driven decisions across BioMarin.

The GDS Data Management Science (DMS) group contributes to Global Data Science by providing complete, correct, and consistent analyzable data at data, data structure and documentation levels following international standards and GCP. The GDS DMS Operations sub-function is responsible for the efficient and effective delivery of complete, correct, and consistently fit-for-purpose data sets for statistical analysis across all clinical development and post-approval programs. The team brings a focus on process improvement through innovation and the application of best practices to the oversight and execution of all program-related data management activities such as Protocol review, Case Report Form (eCRF) development, Data Management Plan development, Data Validation Plan development, requirement specifications, reconciliations, and data validation activities to ensure data integrity and data quality.

SUMMARY DESCRIPTION

The DMS Operations Manager role is a Study Lead role on multiple Clinical Studies. The Manager participates in all study-related data management activities, including Protocol review, eCRF development, Data Management Plan development, Data Validation Plan development, reconciliations, and delivery of complete, correct, and consistently fit-for-purpose study datasets for statistical analysis.

The DMS Operations Manager may also act as Process Improvement / Departmental Initiative contributor, as needed.

KEY RESPONSIBILITIES:

DMS Operations Manager may participate in all, or part of the following activities as delegated by the GDS Data Management Science Operations Program Lead.

Clinical Study Development and Execution

• Comp