Head of Machine Learning

What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?

FL94 Inc., is a privately held, early-stage biotechnology company pioneering Protein Editing. At FL94 we create small molecules that edit protein structure and function to unlock presently undruggable targets and a broad array of novel chemistry modalities. Our platform integrates novel small molecule chemistry and chemoproteomic discovery technologies with machine learning to enable generative design of protein editing chemistries. FL94 is backed by Flagship Pioneering, bringing the courage, vision, and resources to guide FL94 from platform validation to patient impact. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us! 

Position Summary: 

FL94 is seeking a hands-on,n experienced, creative, and visionary Head of Machine Learning. You will be responsible for setting the strategy for, building, and leading a team of data infrastructure and machine learning scientists. The objective of this team is to develop and apply cutting-edge machine learning (ML) paradigms across FL94’s proprietary chemoproteomics and small molecule chemistry data sets to narrow the search space and increase the probability of discovering novel chemistries via generative design. This position is ideal for someone with deep expertise in machine learning, deep learning (particularly for building biologically meaningful representations of chemical structures), and computational chemistry, sciences and who is committed to building leadinga high-preforming performing team.  

Successful candidates will be able to thrive in a fast-paced, action-oriented, team environment and display a clear passion for science and impact. The role offers a unique opportunity to help drive the strategy of an early stage, big concept biotech. The candidate must be an entrepreneurial, highly motivated and purpose driven leader who is able to technically and strategically lead high-performing teams. The successful candidate will have a track record of accomplishments in data science / machine deep learning as well as demonstrated high impact research in academia or industry. S(he) must exhibit excellent leadership, project management, and strong collaboration and communication skills. S(he) should be ready to champion new ideas and lead breakthrough methods development in a very dynamic and innovative environment.  

Key Responsibilities: 

• Build and lead platform and team driving breakthroughs in deep learning applied to computational chemistry 
• Develop the vision and strategic plan for FL94’s machine learning team to drive novel discoveries in small molecule chemistry 
• Own philosophy and strategy behind core machine learning platform technology and applications 
• Define and build a strategy for developing a robust data portal that will enable the application of generative models to proprietary chemoproteomics data 
• Build and lead team to translating small molecule and proteomic drug discovery challenges and datasets into ML problems and areas for application 
• Define team mission and propose org structure and interaction model to ensure for successful execution  
• Oversee the development and prototyping of novel ML algorithms for drug discovery problems 
• Ensure effective training and validation of large deep learning models at scale  
• Identify and act upon new areas of applied research that can further the platform’s ability to have therapeutic impact 
• Work collaboratively in cross-functional chemistry, proteomics, drug discovery and AI/machine learning teams  
• Partner across the organization to align data generation with infrastructure, innovative approaches, and data integration strategies.  
• Communicate strategy, R&D progress to leadership & actively engage in outreach to external advisors 
• Prepare and deliver scientific updates to the executive leadership team, board of directors, and company advisors  
• Assemble and manage machine learning and data science Scientific Advisory Boards 
• Embody FL94’s core mission to enable generative design of protein editing chemistries and live and set a culture that is highly resilient, optimistic, innovative, solutions-oriented, transparent, and inclusive 

Qualifications: 

• A proven leader with a Ph.D. in machine learning, statistics, computer science, mathematical modeling, operations research, or related field computational chemistry, or other highly-technical fields from a recognized higher-education establishment 
• >3-10 years of experience in the ar