Senior Scientist I, Pipeline Development & Targeted Delivery

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

At AbbVie, we are dedicated to solving some of the world’s most complex and serious diseases. Our mission is to develop and deliver advanced therapeutics that change lives. We are looking for talented, passionate, and driven individuals to join our Biotherapeutics and Genetic Medicine (BGM) team. As a Senior Scientist in our siRNA group, you will be part of an innovative team focused on advancing RNA-based therapies that have the potential to revolutionize patient care.

AbbVie is looking for a Senior Scientist I to join our siRNA group within the Biotherapeutics and Genetic Medicine (BGM) department. This role will involve designing and executing innovative experimental approaches to address key scientific challenges related to oligonucleotide therapeutics. The successful candidate will drive scientific innovation, identify new methods and techniques, and collaborate across functions to support the development of novel RNA-based therapies.

Responsibilities

• Lead research efforts within a cross-functional team to advance new therapeutic targets for siRNA-based pipeline development.
• Design and execute in vitro and in vivo proof-of-concept studies to evaluate novel extrahepatic, targeted siRNA delivery platforms across multiple pipeline programs.
• Design and execute receptor expression profiling, ligand–receptor binding, internalization, and trafficking assays.
• Evaluate functional delivery and target knockdown in receptor-positive cells and tissues.
• Provide scientific leadership and expertise in candidate nomination and pipeline development.
• Work independently and maintain a high level of productivity in the laboratory, ensuring efficiency