Scientist (Biochemistry – High Throughput Antibody Production)

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn. 

Job Description

Key Responsibilities

• Manage antibody production campaigns in collaboration w/therapeutic areas, incl. data mgmt, presentation & coordination of assays to be run.
• Execute high throughput molecular cloning & antibody production workflows using automation technologies.
• Lead dvlpmt of new automated liquid handling or analytical workflows.
• Characterize therapeutic proteins using MS, SEC, DSF, ELISA, SDS-PAGE, FACS.

Qualifications

Education & Experience

Must have a Master's in biology, biochemistry or related field & 2 yr research or industry exp in:

(i) Applying molecular biology techniques (PCR, molecular cloning);

(ii) Utilizing sequence analysis tools (Vector NTI, Geneious, Sequencher), graphing software (GraphPad Prism) &statistical analysis (Python);

(iii) Applying cell culture (bacteria, mammalian) & protein purification techniques (AKTA, Protein Maker, Assay MAP);

(iv) Conducting analytical characterization of therapeutic proteins (MS, SEC, DSF, ELISA, SDS-PAGE); and

(v) Conducting statistical (Python) and structure-based (PyMol, Schrodinger Bioluminate) analysis of protein structure and function to predict liabilities and features of interest in antibodies.

Of experience required, must also have 1 yr research or industry exp utilizing and developing methods on liquid handling platforms (Hamilton, Tecan, Dynamic Devices).

Experience may be gained concurrently.

Additional Information

Salary Range: $104,200 - $138,500 per year.

Apply online at https://careers.abbvie.com/en. Refer to Req ID: REF39458D. 

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