Scientist, Process Development

The Role:

This role is an exciting opportunity to be a part of the drug product process development group located in a modern state-of-the-art facility called the Moderna Technology Center (MTC), Norwood, MA.  This renovated center of excellence houses a wide variety of disciplines, which includes process development, scale-up, and analytical development. The role reports to a Principal Scientist and is a multidiscipline position that involves investigating lipid nanoparticle process development with established and novel analytical techniques.  The individual in this role will be a highly skilled, talented, and motivated associate. They will participate in performing biochemical and biophysical characterization (HPLC, cIEF, light scattering, particle characterization, spectroscopy, calorimetry) of lipid nanoparticles; exploring/developing innovative PAT for advanced process control/characterization. Pertinent experience involves developing and performing analytical, molecular, biochemical, biophysical and/or cellular assays. Prior industry experience in formulation or analytical development is desired.   

Here’s What You’ll Do:

• Develop novel chromatography to support the process development of Lipid Nanoparticles

• Perform analytical testing supporting process development and product release, including spectroscopic, chromatographic, biophysical, and molecular biology techniques

• Perform big data analysis and trending with programming language.

• Optimize process development with downstream and prequalify analytical techniques to characterize lipid nanoparticles to support process development and formulation design. 

• Manage sample requests and data reporting within a digitally-integrated workflow

• Present updates on research and development findings internally in a timely fashion 

• Maintain thorough electronic lab notebooks and documentation records

• Collaborate within departmental teams, contribute to deliverables, drive development activities in a cross-functional environment, and engage in team discussion on issue resolution

Here’s What You’ll Bring to the Table:

• Bachelors with at least 8 years of work experience or MS with  at least 5 years or Ph.D

• Hands on experience with chromatography analytical experience (e.g. AKTA-HPLC with MALS, UV, fluorescence, LC/MS, CE, GC, DLS)

• Great communication skills and the ability to write detailed technical reports

• Strong interpersonal skills with an eagerness to support colleagues in Research, AD, CMC, Manufacturing and Process Development

• Experience in nucleic acid drug development (e.g. DNA, RNA, oligonucleotides)

• Familiarity with chromatographic techniques for characterizing nanoparticles (e.g. SEC/FFF-MALS, IEX, RP, HIC)

• Experience with various biophysical and light scattering techniques (e.g. DLS, NTA, Coulter Counter, laser diffraction, microscopy)

• Statistical knowledge and proficiency with data visualization/analysis/modeling software (e.g. GraphPad, Microsoft Excel, JMP, TIBCO Spotfire)

• Preferred: Experience with nanoparticle formulations

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

• Highly competitive and inclusive medical, dental and vision coverage options
• Flexible Spending Accounts for medical expenses and dependent care expenses
• Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
• Family care benefits, including subsidized back-up care options and on-demand tutoring
• Free premium access to fitness, nutrition, and mindfulness classes 
• Exclusive preferred pricing on Peloton fitness equipment
• Adoption and family-planning benefits
• Dedicated care coordination support for our LGBTQ+ community
• Generous paid time off, including:
  •    Vacation, sick time and holidays
  •    Volunteer time to participate within your community
  •    Discretionary year-end shutdown
  •    Paid sabbatical after 5 years; every 3 years thereafter
• Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
• 401k match and Financial Planning tools
• Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
• Complimentary concierge service including home services research, travel booking, and entertainment requests
• Free parking or subsidized commuter passes
• Location-specific perks and extras!

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are