Product Director, Oncology

Company Description

Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook.

Job Description

The Guardant Health Product Director, Oncology, reports to the Senior Director of Product Management. This role will be a product management focused role responsible for driving market evolution in one of Guardant Health’s leading oncology products. This is a pivotal role for a strategic and execution-driven leader who thrives at the intersection of product innovation, clinical impact, and commercial growth. The Product Director, Oncology will lead the product strategy, roadmap execution, and commercial readiness for one of Guardant’s most strategic offerings. This role will have the opportunity to shape how a high-impact diagnostic enters standard of care and influence how to accelerate adoption in a growing MRD (Minimal/Molecular Residual Disease) market and will work closely with technical, clinical, medical, and commercial teams to drive product’s value proposition, evidence strategy, and product-market fit across indications.

Responsibilities

• Lead end-to-end execution of the designated product roadmap—including new features, workflow enhancements, and indication expansion.
• Serve as the subject matter expert in the field and drive future concepts for product development.
• Drive product launch execution through phase gates, commercial excellence programs and drive overall product readiness initiatives.
• Translate strategic goals into executable plans with clear timelines, KPIs, and milestones tied to business outcomes.
• Key to success in this role requires best-in-class organizational skills and being responsible for results that drive impact across functions.
• Work cross-functionally with R&D, clinical development, regulatory, and commercial to drive product delivery from concept to launch.
• Identify and resolve executional risks to ensure timely and successful product development and rollout. Serve as the external spokesperson for the organization.
• Engage directly and through sales/marketing teams with oncologists, NPs, practice managers, and integrated delivery networks (IDNs) to understand MRD use cases and pain points.
• Engage with external BioPharma customers to navigate their MRD (Minimal/Molecular Residual Disease) product needs, requirements and workflow.
• Define and prioritize product capabilities that align with clinical workflows and improve user experience.

• Ensure the product aligns with both physician needs and payer expectations, including actionable results and clinical utility.

• Own the business case for one of Guardant Health’s leading products, including pricing, COGS, and contribution to Guardant’s overall oncology portfolio.
• Monitor competitive activity in MRD (Minimal/Molecular Residual Disease) and adjacent markets, and shape Guardant Health’s product market differentiation strategy accordingly.
• Partner with Market Access and Medical Affairs teams to ensure the evidence plan supports reimbursement and payer acceptance.

• Collaborate with Sa