Senior Scientist - Enzyme Process Development

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Position Summary:

We are looking for a talented individual to join our enzyme purification process development team. The chosen candidate will have laboratory experience with protein biochemistry and assays and will function closely with a team of scientists to design processes for manufacture of proteins and related reagents.

Responsibilities:

• Develop robust, scalable protein purification processes suitable for transfer to manufacturing
• Purify proteins using column chromatography and filtration techniques
• Perform functional and physical assays to assess protein purity and stability
• Develop, generate, and verify buffer systems to support specific design requirements
• Thoroughly and accurately document experiments as they are performed
• Curate samples and generate process development reports
• Help troubleshoot unexpected or challenging results within a team
• Optimize and stress test process designs to ensure robust performance
• Analyze, summarize, and present results to teams to drive design decisions and improvements

Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs

Requirements:

• BS with minimum 5 years, MS with minimum 3 years, or PhD with 0-3 years experience in Biochemistry, Molecular Biology, Genetics, Microbiology, Chemistry, Chemical Engineering, Biomedical Engineering, or related field
• Experience in analyzing proteins and nucleic acids using techniques such as SDS-PAGE, agarose gel electrophoresis, UV/Vis spectroscopy, fluorescence-based assays, or protein or nucleic acid quantitation
• Familiarity with column chromatography techniques such as IMAC, affinity, ion exchange, hydrophobic interaction, or size exclusion chromatography
• Familiarity with filtration techniques such as microfiltration, depth filtration, or tangential flow filtration
• Experience with automated purification using Cytiva Akta systems and Unicorn software is a plus
• Experience with basic buffer formulation for proteins and understanding of the chemical properties of salts, chelators, biological buffers, and reducing agents
• Excellent written and oral communication skills
• Excellent troubleshooting, organizational, and analytical abilities
• Excellent time-management skills
• Comfort with ambiguity and a fast-paced, highly collaborative work environment
• Able to pivot and quickly shift work focus according to business needs

The estimated base salary range for the Senior Scientist - Enzyme Process Development role based in the United States of America is: $81,800 - $122,600. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. Compensation decisions are dependent on several factors including, but not limited to, an individual’s qualifications, location where the role is to be performed, internal equity, and alignment with market data. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.

At Illumina, we strive to foster a diverse and inclusive workplace by cultivating an environment in which everyone contributes to our mission. Built on a strong foundation, Illumina has always been rooted in openness, collaboration, and seeking alternative views and perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and demonstrate our collective commitment to diversity and inclusion in the communities we live and work. We are proud to be an equal opportunity