Associate Director, Oncology, Translational Medicine

The Role:

Moderna is seeking a Translational Medicine Expert to play a pivotal role in bridging the gap between preclinical research and clinical application to accelerate the development of groundbreaking therapies. This Translational Medicine role is focusing on next generation mRNA therapeutics in Oncology. The role will work with a cross functional team (medical directors, nonclinical and discovery research scientists, regulatory, clinical operations) on the translational strategy for clinical development and regulatory approvals. Position is ideally based in Cambridge, MA headquarters.

Here's What You’ll Do:

• Work across Research and Development to define translational medicine strategy across oncology portfolio, including making recommendation regarding endpoints, study design, safety evaluations and dose selections.

• Identify and seek to validate novel endpoints for early (pre-POC) decision making and identify patient or target population stratification strategies to support rapid demonstration of safety and efficacy.

• Develop and lead reverse translational strategy to enable research and development.

• Work closely with other matrix functional areas to define key aspects of the integrated development plans, including the assessment of medical need, proposal of clinical development pathways, and review of preclinical data for clinical implications.

• Collaborate with Biomarkers Lead(s) to define strategy for clinical stage programs, including design and writing, as well as authoring the biomarker sections of Investigator Brochures, Clinical Study Protocols and Reports, program documents, regulatory submissions, and responses (INDs/CTAs) as well as co-authoring, assisting, and supporting the development of publications, abstracts, and presentations.

• Partner with biostatisticians and biomarker experts to ensure high-quality data to support analysis, interpretation, and reports for internal decision-making.

• Works with program team leads to ensure efficient implementation of all key deliverables and provides frequent project status updates to the cross-functional development teams.

Here’s What You’ll Bring to the Table:

• Advanced scientific degree in a relevant scientific field (M.D., Ph.D., Pharm.D.), with minimum 5 years of relevant work experience developing biomarker and translational medicine strategies.

• A strong background in Oncology, Immunology, and experience in translational medicine

• Proficiency in emerging diagnostic and predictive biomarker technologies is a plus.

Desired Skills and Competencies:

• Innovative problem-solving skills with a focus on complex scientific challenges.

• Advanced communication skills for effective negotiation and stakeholder engagement.

• Demonstrated track record in leading cross-functional teams and work streams (e.g., translational medicine, biostatistics, regulatory, pre-clinical pharmacology, clinical and immunogenicity assay development)

• Understanding of the entire Oncology development process, including clinical and non-clinical study design, use of immunologic surrogates, assay development and importance of target product profile.

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

• Highly competitive and inclusive medical, dental and vision coverage options
• Flexible Spending Accounts for medical expenses and dependent care expenses
• Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
• Family care benefits, including subsidized back-up care options and on-demand tutoring
• Free premium access to fitness, nutrition, and mindfulness classes 
• Exclusive preferred pricing on Peloton fitness equipment
• Adoption and family-planning benefits
• Dedicated care coordination support for our LGBTQ+ community
• Generous paid time off, including:
  •    Vacation, sick time and holidays
  •    Volunteer time to participate within your community
  •    Discretionary year-end shutdown
  •    Paid sabbatical after 5 years; every 3 years thereafter
• Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
• 401k match and Financial Planning tools
• Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
• Complimentary concierge service including home services research, travel booking, and entertainment requests
• Free parking or subsidized commuter passes
• Location-specific perks and extras!

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technol