Director, HTA, Value & Evidence, Prostate Cancer - Orgovyx

ROLE SUMMARY

The Director, HTA, Value & Evidence (HV&E) US Genitourinary Cancer (GU)/Orgovyx will support the strategic goals of the Oncology division driving HTA, Value & Evidence development to support optimal patient access & utilization for GU cancer medicines, particularly Orgovyx.  This role will require functioning across an alliance with the NDA holder for Orgovyx, as well as developing Value & Evidence US strategy peri and post-launch, for GU products.

This role directly impacts the ability to achieve US scientific & business objectives, working directly with and supporting alliance strategy through robust evidence development relevant to achieve optimal patient access. This will be achieved by rigorously  demonstrating the value of our GU cancer medicines portfolio (with particular focus on Orgovyx). The HV&E Director will be responsible for developing and executing against the US evidence generation strategy in close collaboration with alliance counterparts, US Medical Strategy, GU Global HV&E Global Access & Value teams including direct oversight of evidence generation activities and publications & pull-through dissemination of technical deliverables.

ROLE RESPONSIBILITIES

• With a significant amount of autonomy, lead the development of the US-specific Value & Evidence generation strategy to support the value of Orgovyx/GU cancer products in the Oncology Business in close partnership with Pfizer cross-functional & cross-alliance matrix teams.

• Lead the coordination of input from US Medical, Global HV&E, GAV and other cross-functional partners on evidence gaps & needs and ensure that the input is appropriately incorporated to develop and integrate the evidence strategy to support US market access needs through lifecycle.

• Collaboratively ensure quality standards and data integrity of all projects across the alliance (projects led by either company).

• Provide strategic input into real-world study designs (eg:, patient populations, comparators, endpoints) to enable successful negotiations, reimbursement, and appropriate patient access and drug utilization with US payer and regulatory decision makers.

• Lead the design and execution of health economics & outcomes research (HEOR) studies (eg:, network meta-analyses, non-interventional studies) from concept through publication.  

• Lead the timely development of US peri & post-launch deliverables including updates to AMCP dossiers, payer value propositions, value & evidence strategysystematic literature reviews, economic models, and innovative tools to successfully support reimbursement and access requirements in conjunction with the global team.

• Partner with internal stakeholders to ensure appropriate customer facing dissemination of HEOR materials per regulatory guidance and internal SOPs.

• Develop strategic partnerships and research collaborations with key external experts, organized customers, healthcare policy makers, payers, and various academic and community oncology settings to support asset strategies.

• Represent Pfizer at scientific and academic meetings.

• Execute all projects in an ethically and SOP compliant manner.

BASIC QUALIFICATIONS

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

• Graduate degree required (e.g. MSc, MPH, PhD)

• 9+ years of experience with MSc/MPH/MBA degree; 7+ years with PharmD/PhD in HEOR or relevant related fields (health economics, epidemiology, health services research, or other research-focused public health field).

• Demonstrated in depth understanding of fundamental health services research methods and tools, including health economic modeling, patient-reported outcomes, statistics, and real-world evidence studies including technical and methodological aspects of registries and observational study design, implementation, analysis and interpretation.

• Skilled in functioning within a matrix organization where managing through influence & subject matter expertise is required

• Experience with HTA/Quasi HTA organizations like ICER and other HTA groups is desirable

• Excellent interpersonal skills required: ability to understand and respond to multiple internal and external customers

• Excellent oral and written English communication skills required

• Demonstrated ability to assess anticipated value for projects/programs to ensure alignment to busin