Senior Scientist I, Mass Spectrometry

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

The Analytical Research & Development team is seeking a talented, highly motivated candidate with experience in the characterization of peptide and oligonucleotide biomolecules.  This is a laboratory-based role, and the successful candidate will be responsible for designing, developing, and implementing analytical methods for the characterization of peptides and oligonucleotides with an emphasis on mass spectrometry-based methods.  Candidate should possess an understanding of their core discipline and use that expertise to support early phase development of drug substance and drug product and collaborate across the global Analytical R&D organization and with cross-functional partners such as Pre-Clinical Safety (PCS), Process Chemistry, Process Engineering, Drug Product Development (DPD), Quality Assurance (QA), and CMC-Regulatory. 

Responsibilities:

• Utilize cutting-edge mass spectrometry techniques, including high-resolution MS, MS/MS, ion mobility-MS, and 2DLC-MS, to characterize small molecule, peptide, and oligonucleotide drug products, active pharmaceutical ingredients, intermediates, starting materials, and impurities.
• Identify, develop, and implement novel analytical methods for the characterization of peptide and oligonucleotide pharmaceuticals with an emphasis on LC-MS and biophysical characterization to drive discovery projects through the research and development pipeline.
• Be responsible for leading the structure elucidation aspects of a project while collaborating with cross-functional project teams to advance programs through the development pipeline.
• Support new product development with advanced method development and validations, technical transfer pac