Specialist, 3DT Biofabrication Scientist (Cambridge, MA)

Job Description

We are seeking a Scientist II who is passionate about developing complex in vitro microphysiological organ-on-chip systems (MPS) and bioprinted models for drug discovery and development. In this role, the scientist will perform hands-on experimentation and provide support to advance the team’s biofabrication efforts.

This position is based on-site in Cambridge, MA, supporting day-to-day laboratory workflows and assisting with model development within a collaborative research environment.

Key Responsibilities

• Support the biofabrication and maintenance of microphysiological systems and bioprinted models.

• Perform routine mammalian cell culture while maintaining a high level of aseptic technique.

• Prepare and handle hydrogels/ECM for use in 3D culture (MPS and bioprinted) platforms.

• Assist in immunofluorescence staining, imaging, and analysis workflows.

• Reconstitute, aliquot, and prepare reagents and media.

• Execute multi-step experimental protocols and workflows.

• Document experimental procedures, observations, and results in electronic lab notebook.

• Assist with inventory management, ordering, and general lab maintenance.

• Support both general and project-specific laboratory operations as project needs evolve.

• Collaborate across different functional teams/locations.

Required Education: High School Diploma or GED required.  Bachelor’s Degree or Master’s Degree preferred. (B.S./B.A. in Bioengineering, Biology, Biomedical Engineering, Cell & Molecular Biology, Immunology, or a related field with minimum of 1 year of relevant experience or Master’s Degree)

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Required Experience and Skills

• Minimum of 2 years of experience in mammalian cell culture and aseptic technique.

• Experience preparing and handling biomaterials or hydrogels for 3D culture applications.

• Experience working with MPS models, bioprinted platforms, or other 3D cell culture technologies.

• Familiarity with basic microscopy techniques for assessing cell health and experimental progress.

• Strong attention to detail, organizational skills, and accurate documentation practices.

• Demonstrated ability to execute experimental protocols and work with collaborators.

• Ability to work on-site, follow established protocols, and meet deadlines.

• Enthusiastic, self-motivated, and eager to learn new workflows.

Preferred Experience and Skills

• Experience with stem cell culture or differentiation workflows.

• Experience with stem cell-derived organoid models.

• Experience working with MIMETAS organ-on-chip, or similar high throughput, platform.

• Experience working in pharmaceutical drug discovery or development.

• Data analysis experience using Matlab, R, and/or Python.

• Experience with nucleofection.

#eligibleforerp

MSJR

Required Skills:

3D Cell Culture, 3D Cultures, Aseptic Technique, Bioprinting, Bioproduction, Mammalian Cell Culture

Preferred Skills:

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