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GU
Staff Scientist
GuidehouseUnited Statesfull_timeVerifiedPosted 6 Aug 2026
💰 $163,000/yr($98,000/yr – $163,000/yr)
About the role
<p><b><u>Job Family</u>:</b></p>Scientist<p><br/><b><u>Travel Required</u>:</b></p>None<p><br/><b><u>Clearance Required</u>:</b></p>Ability to Obtain Public Trust<p></p><p></p><p><b><u>What You Will Do</u>:</b></p><p><span>We are currently searching for a Staff Scientist to provide laboratory leadership and support services to perform interdisciplinary and collaborative research from bench to beside with the National Heart, Lung, and Blood Institute (NHLBI). This is a full-time, on-site opportunity in Bethesda, MD.<span> </span></span></p><ul><li><p>Combine biochemical, molecular, cellular, genetic, and quantitative approaches to investigate fundamental biological processes across a range of organisms, including fish, <span>flies, mice, mammals,</span> microbes, and viruses.</p></li><li><p>Gain an understanding on how cells sense, respond, and adapt to a variety of stress conditions, including nutrient deprivation, organelle damage, and pathogen infection.</p></li><li><p>Address how alterations in mTOR, TFEB, TFE3, and <span>lysosomal function lead</span> to human disease.</p></li><li><p><span>Seek to identify potential</span> sites for therapeutic intervention suitable for further evaluation in translational and clinical research efforts.</p></li><li><p>Contribute to training and mentoring of all laboratory members.</p></li></ul><p><br/><b><u>What You Will Need</u>:</b></p><ul><li><p>PhD with at least TWO (2) years of postdoctoral research experience in molecular biology, cellular biology, biochemistry, or related field OR</p></li><li><p>Master’s degree with at least FIVE (5) years of intensive, hands-on research experience in molecular biology, cellular biology, biochemistry, or related field in lieu of PhD</p></li><li><p>Must have a mastery of Zebrafish models with skills such as husbandry, genetic crossing, and genotyping protocols. </p></li><li><p>Must have a have a strong publication record.</p></li><li><p>Experience working with other animal models.</p></li><li><p>Expertise in cellular biology and microscopy imaging. </p></li><li><p><span>Must be able to obtain and maintain a Federal or DoD Public Trust. Candidates must receive approved adjudication of their Public Trust prior to onboarding with Guidehouse. Candidates with an active Public Trust or existing suitability are preferred.</span></p></li></ul><p><br/><b><u>What Would Be Nice To Have</u>:</b></p><ul><li><p>Advanced skills in light microscopy are strongly desired.</p></li><li><p>Knowledge <span>of organelle cell</span> <span>biology (lysosomes,</span> autophagy, intracellular <span>trafficking), and</span> a commitment to conducting related high-quality research. </p></li><li><p>Able to work independently and in a team setting.</p></li><li><p>Excellent verbal and written communication abilities.</p></li><li><p>Outstanding interpersonal and time management skills.</p></li><li><p>Demonstrated experience in staff training and mentoring.</p></li></ul><p></p><p></p>The annual salary range for this position is <span>$98,000.00-$163,000.00.</span> Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.<p><br/><u><b>What We Offer:</b></u></p><p>Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.</p><p></p><p>Benefits include:</p><ul><li><p>Medical, Rx, Dental & Vision Insurance</p></li><li><p>Personal and Family Sick Time & Company Paid Holidays</p></li><li><p>Parental Leave</p></li><li><p>401(k) Retirement Plan</p></li><li><p>Group Term Life and Travel Assistance</p></li><li><p>Voluntary Life and AD&D Insurance</p></li><li><p>Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts</p></li><li><p>Transit and Parking Commuter Benefits</p></li><li><p>Short-Term & Long-Term Disability</p></li><li><p>Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities</p></li><li><p>Employee Referral Program</p></li><li><p>Corporate Sponsored Events & Community Outreach</p></li><li><p>Care.com annual membership</p></li><li><p>Employee Assistance Program</p></li><li><p>Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)</p></li><li><p>Position may be eligible for a discretionary variable incentive bonus</p></li></ul><p></p><p><u><b>About Guidehouse</b></u></p><p>Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.</p><p></p><p>Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance
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