Director, GVAS AMKD Lead

Job Description

Director, Global Value Access & Strategy, AMKD

Location: Boston, MA (3 days onsite, 2 days remote weekly)

Vertex operates at the forefront of scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF) as well as Casgevy, a gene therapy for sickle cell disease and beta-thalassemia.  Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in Pain, APOL-1 mediated kidney disease (AMKD), and cell therapies for Type 1 diabetes, among others. 

Overview:

Market Access is a key commercial function that ensures transformative Vertex therapies are appropriately funded and ultimately make it into the hands of the patients around the world.  The GVAS (Global Value & Access Strategy) team works cross-functionally and across regions to ensure the payer view is represented in commercial and development plans across the lifecycle.  We are driven by a desire to deliver groundbreaking pricing & reimbursement solutions to allow our medicines to reach patients faster than ever before.

The Director, GVAS role will serve as Market Access Lead for our APOL-1 mediated kidney disease (AMKD) portfolio, with a focus on lead asset inaxaplin.  Pipeline products for AMKD are in development to treat chronic kidney diseases in patients with APOL-1 genetic risk alleles.  The individual will be responsible for leading the development of Global Market Access strategies, as well as co-lead for the Global Commercial Team. The role reports to Sr Director, Genetic Kidney Disease lead. 

Key Responsibilities:

• Responsible for Global payer strategic planning to support value and access optimization for lead AMKD asset inaxaplin

  • Lead development of Market Access strategies and core Global P&R deliverables operating within the cross-functional, cross-regional commercialization process

    • Responsible for Global payer strategic planning to support value and access optimization; lead development of Global Payer Plan which integrates value evidence generation, strategic pricing, value communications, stakeholder engagement to support successful reimbursement and pricing

  • Accountable for ensuring the market access and payer perspective is reflected in cross-functional strategies (e.g. commercial, product development, regulatory affairs)

  • Ensure evidence prioritization required to capture value, support a differentiated target product profile (TPP), and ensure local pricing and access

  • Support strategies with deep functional knowledge, in-depth market research, environmental data & analogs

  • Inform financial forecasts

  • Partner with Health Economics & Outcomes Research (HEOR), Real-World Evidence (RWE) and Global Marketing to ensure robust value proposition and integrated evidence plans are optimized to support global market access and reimbursement

• Co-lead AMKD Global Commercial Team (with Global Marketing) and work cross-functionally and cross-regionally to develop optimal commercial strategies

  • The Global Commercial Team facilitates development of a commercial strategy in order to maximize the lifetime value of the asset globally; is the primary hub for alignment and input into the Disease Strategy Team

  • This role should ensure collaboration and drive alignment across Global Commercial Team and leadership to integrate market access strategy and ensure resourcing for commercial success

• Support P&MA capability building and thought leadership projects that advance knowledge of and readiness for the rapidly evolving Global payer environment

• Maintain industry awareness and proactively address changes in market trends, competition, product acceptance and new product releases and adjust Market Access plans accordingly

• Collaborate closely with HEOR, International P&R, Corporate Affairs, US Market Access, Countries, Marketing and Clinical Development counterparts to ensure value and access optimization

Education and Experience:

• BA/BS in field of study requiring quantitative analysis; advanced degree preferred

• 8+ years of direct biotechnology / pharmaceutical industry experience and/or payer experience

• Deep working knowledge of both US and ex-US healthcare systems required; experience in comparable Global role considered a plus

• Experience in leading cross-functional teams required

• Experience in specialty and/or rare disease access models preferred

• Demonstrated ab